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术后炎性神经病变:一种未得到充分认识但至关重要且可治疗的术后神经病变病因。

Post-Surgical Inflammatory Neuropathy: An Underappreciated but Critical and Treatable Cause of Postoperative Neuropathy.

作者信息

Godlewski Christopher A, Kalagara Hari, Vazquez Do Campo Rocio, Northern Theresa, Kukreja Promil

机构信息

Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.

Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, USA.

出版信息

Cureus. 2020 Dec 5;12(12):e11927. doi: 10.7759/cureus.11927.

Abstract

The diagnosis and management of postoperative nerve injury can be a challenging and frustrating proposition for the patient, surgeon, and anesthesia provider. Unfortunately, in many cases, the true etiology is never elucidated and the injury is ascribed to positioning or a nerve block with "expectant management" being the order of the day, which can result in persistent disability for the patient. However, there is a rare subset of disorders affecting the nervous system that can masquerade as a peripheral nerve injury that warrants further investigation of risk factors and co-morbidities when other common causes of nerve injury are ruled out. We describe a patient with rheumatoid arthritis that underwent revision hip arthroplasty and presented almost immediately in the postoperative period with what was initially diagnosed as femoral nerve palsy. Further diagnostic workup later revealed that she had suffered from postoperative inflammatory neuropathy resulting in lumbosacral plexus injury and not a discrete nerve injury. Had the true cause been identified early enough, treatment with corticosteroids could have been initiated in an attempt to mitigate and perhaps reverse the progress of the neuropathy. We present this cautionary tale to remind practitioners to continue to be vigilant and consider more esoteric and unconventional diagnoses in the workup of perioperative neuropathies.

摘要

术后神经损伤的诊断和处理,对患者、外科医生及麻醉医生来说,可能是一项具有挑战性且令人沮丧的任务。不幸的是,在许多情况下,真正的病因从未得到阐明,损伤被归咎于体位或神经阻滞,“观察等待”成为日常处理方式,这可能导致患者持续残疾。然而,有一小部分罕见的影响神经系统的疾病,可能伪装成周围神经损伤,在排除其他常见神经损伤原因后,需要进一步调查危险因素和合并症。我们描述了一名类风湿关节炎患者,该患者接受了髋关节翻修置换术,术后几乎立即出现最初被诊断为股神经麻痹的症状。进一步的诊断检查后来发现,她患有术后炎性神经病变,导致腰骶丛损伤,而非单一神经损伤。如果能足够早地确定真正病因,就可以开始使用皮质类固醇进行治疗,试图减轻并可能逆转神经病变的进展。我们讲述这个警示故事,是为了提醒从业者在围手术期神经病变的检查过程中要继续保持警惕,并考虑更罕见和非常规的诊断。

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