Department of Anesthesia and Intensive Care Medicine, Copenhagen University Hospital: Bispebjerg, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Denmark.
Reg Anesth Pain Med. 2012 May-Jun;37(3):294-301. doi: 10.1097/AAP.0b013e31824c20a9.
The ability of transversus abdominis plane (TAP) blocks to anesthetize the upper abdomen remains debatable. We aimed to describe the local anesthetic distribution following ultrasound-guided TAP blocks with repeated magnetic resonance imaging investigations and to relate this to the resulting dermatomal anesthesia.
Eight volunteers were included in a randomized, observer-blinded study. Sixty milliliters of ropivacaine 0.375% was administered: 1 injection of 30 mL as a lateral classic TAP block, followed by a sham upper intercostal TAP block, and on the contralateral side, 2 separate 15-mL injections at the upper intercostal and lateral classic TAP plexuses, respectively. The primary outcome measure was magnetic resonance imaging-assessed area expansion of all injectates over a 6-hr period. Dermatomal anesthesia and sequential serum ropivacaine levels were recorded at the same time intervals.
All injectate areas expanded in a statistically significant manner in the anterior abdominal wall. Lateral classic TAP blocks with 30-mL injectates did not extend into the upper intercostal TAP plexus. The dual 15-mL injectates on the other hemiabdomen remained within the upper intercostal and lateral classic TAP compartments and resulted in significantly (P < 0.018) more widespread dermatomal anesthesia. Measured serum ropivacaine concentrations were below the potential level of toxicity.
Magnetic resonance imaging analysis revealed a significant time-dependent expansion of injectates. Magnetic resonance imaging and the degree of dermatomal anesthesia confirmed that the upper and lateral TAP compartments do not appear to communicate. Separate injections at the upper intercostal and lateral classic TAP plexuses are necessary to block the entire abdominal wall.
腹横肌平面(TAP)阻滞能否麻醉上腹部仍存在争议。本研究旨在通过重复磁共振成像(MRI)检查描述超声引导下 TAP 阻滞时局部麻醉药的分布,并将其与产生的皮区麻醉相关联。
8 名志愿者参与了这项随机、观察者设盲的研究。志愿者接受了 60ml 0.375%罗哌卡因的注射:1 次 30ml 作为外侧经典 TAP 阻滞,随后在上肋间进行 sham TAP 阻滞,对侧分别在肋间和外侧经典 TAP 丛进行 2 次 15ml 注射。主要观察指标为所有注射物在 6 小时内通过 MRI 评估的面积扩张。同时记录皮区麻醉和序贯血清罗哌卡因水平。
所有注射物在前腹壁均呈统计学显著扩张。30ml 注射的外侧经典 TAP 阻滞未延伸至上肋间 TAP 丛。对侧的双侧 15ml 注射物仍局限于肋间和外侧经典 TAP 间隙,导致显著(P < 0.018)更广泛的皮区麻醉。测量的血清罗哌卡因浓度低于潜在毒性水平。
MRI 分析显示注射物有明显的时间依赖性扩张。MRI 和皮区麻醉程度证实上侧 TAP 间隙和外侧 TAP 间隙似乎没有相通。要阻滞整个腹壁,需要在上肋间和外侧经典 TAP 丛分别进行注射。