Ahsan Tasnim, Rani Bharta
Diabetes and Endocrinology, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Diabetes & Endocrinology, Orthopaedic & Medical Institute, Karachi, PAK.
Cureus. 2020 Dec 7;12(12):e11961. doi: 10.7759/cureus.11961.
The spectrum of coronavirus disease (COVID-19) continues to evolve as time passes. In the majority of those infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), apart from fever, respiratory and gastrointestinal symptoms, involvement of other systems, such as cardiovascular and neurological system has also been described. Association between COVID-19 disease and a multisystem inflammatory syndrome in children and adolescents (MIS-C) has now been well defined. However, in adults there are sparse case reports describing a similar phenomenon. This has led to the development of preliminary case definitions for this disease, based on clinical manifestations, laboratory criteria and recent SARS-CoV-2 exposure or infection. Here we present a case of 28-year-old man who presented with high grade fever, rash, gastrointestinal and neurological symptoms fulfilling the criteria of MIS-C with a prior COVID-19 infection and recovered completely in 6 weeks after receiving steroid therapy.
随着时间的推移,冠状病毒病(COVID-19)的症状谱仍在不断演变。在大多数感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的患者中,除了发热、呼吸道和胃肠道症状外,还出现了其他系统受累的情况,如心血管系统和神经系统。目前,COVID-19疾病与儿童和青少年多系统炎症综合征(MIS-C)之间的关联已得到明确界定。然而,在成人中,仅有少数病例报告描述了类似现象。这促使人们根据临床表现、实验室标准以及近期的SARS-CoV-2暴露或感染情况,制定了该疾病的初步病例定义。在此,我们报告一例28岁男性患者,该患者出现高热、皮疹、胃肠道和神经系统症状,符合MIS-C标准,且之前有COVID-19感染史,在接受类固醇治疗后6周完全康复。