急性脑膜炎球菌血症的预后评分

Prognostic score in acute meningococcemia.

作者信息

Emparanza J I, Aldamiz-Echevarria L, Perez-Yarza E G, Larrañaga P, Jiminez J L, Labiano M, Ozcoidi I

机构信息

Pediatric Intensive Care Unit, Ntra. Sra. de Aranzazu Children's Hospital, San Sebastian, Spain.

出版信息

Crit Care Med. 1988 Feb;16(2):168-9. doi: 10.1097/00003246-198802000-00015.

DOI:10.1097/00003246-198802000-00015

PMID:3342629

Abstract

A prognostic score for children with acute meningococcemia is proposed. We reviewed 176 consecutive patients with acute meningococcemia with ten fatalities admitted to our pediatric ICU in the last 3 yr. The score was obtained from patients in shock, using a stepwise linear discriminant analysis of 18 clinical and laboratory variables on admission. Nine variables showed a significant discriminant power in predicting survival and death: coma, base excess, platelets, glucose, temperature, WBC, sex, purpura, and CSF. The score predicted survival in 100% and death in 91%. The predictive values were significantly better than evaluation by the frequencies of the usual clinical and laboratory variables.

摘要

提出了一种针对急性脑膜炎球菌血症患儿的预后评分。我们回顾了过去3年在我们儿科重症监护病房收治的176例连续性急性脑膜炎球菌血症患者，其中10例死亡。该评分来自休克患者，通过对入院时18项临床和实验室变量进行逐步线性判别分析得出。九个变量在预测生存和死亡方面显示出显著的判别能力：昏迷、碱剩余、血小板、葡萄糖、体温、白细胞、性别、紫癜和脑脊液。该评分预测生存的准确率为100%，预测死亡的准确率为91%。其预测价值显著优于通过常见临床和实验室变量的频率进行的评估。