Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.
Department of Psychiatry, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.
J Alzheimers Dis. 2021;79(3):1213-1226. doi: 10.3233/JAD-201275.
Having accurate, up-to-date information on the epidemiology of mild cognitive impairment (MCI) and dementia is imperative.
To determine the prevalence of MCI and dementia in Norway using data from a large population-based study.
All people 70 + years of age, n = 19,403, in the fourth wave of the Trøndelag Health Study (HUNT4) were invited to participate in the study HUNT4 70 + . Trained health personnel assessed participants using cognitive tests at a field station, at homes, or at their nursing home. Interviewers also completed a structured carer questionnaire in regard to participants suspected of having dementia. Clinical experts made diagnoses according to DSM-5 criteria. We calculated prevalence weighing the data to ensure population representativeness.
A total of 9,930 (51.2%) of the possible 19,403 people participated, and 9,663 of these had sufficient information for analysis. Standardized prevalence of dementia and MCI was 14.6% (95% confidence interval (CI) 13.9-15.4) and 35.3% (95% CI 34.3-36.4), respectively. Dementia was more prevalent in women and MCI more prevalent in men. The most prevalent dementia subtype was Alzheimer's disease (57%). By adding data collected from a study of persons < 70 years in the same region, we estimate that there are 101,118 persons with dementia in Norway in 2020, and this is projected to increase to 236,789 and 380,134 in 2050 and 2100, respectively.
We found a higher prevalence of dementia and MCI than most previous studies. The present prevalence and future projections are vital for preparing for future challenges to the healthcare system and the entire society.
拥有关于轻度认知障碍（MCI）和痴呆症的准确、最新的流行病学信息至关重要。
使用来自一项大型基于人群的研究的数据，确定挪威 MCI 和痴呆症的患病率。
邀请所有 70 岁以上的人（n=19403 人）参加第四次特隆赫姆健康研究（HUNT4）的第四波研究 HUNT4 70+。经过培训的健康人员在现场站、家中或养老院使用认知测试评估参与者。访谈者还根据 DSM-5 标准完成了有关疑似痴呆症患者的护理人员问卷。临床专家根据 DSM-5 标准进行诊断。我们通过加权数据来计算患病率，以确保人口代表性。
共有 19403 人（可能人数的 51.2%）中的 9930 人（51.2%）参加了研究，其中 9663 人的数据足以进行分析。痴呆症和 MCI 的标准化患病率分别为 14.6%（95%置信区间（CI）13.9-15.4）和 35.3%（95%CI 34.3-36.4）。女性中痴呆症更为常见，男性中 MCI 更为常见。最常见的痴呆症亚型是阿尔茨海默病（57%）。通过添加来自同一地区的一项研究中收集的小于 70 岁人群的数据，我们估计 2020 年挪威有 101118 人患有痴呆症，预计到 2050 年和 2100 年，这一数字将分别增加到 236789 人和 380134 人。
我们发现痴呆症和 MCI 的患病率高于大多数先前的研究。目前的患病率和未来的预测对于为未来医疗保健系统和整个社会面临的挑战做好准备至关重要。
