Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, USA.
Department of Maternal and Child Health, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
J Diabetes. 2021 Apr;13(4):299-306. doi: 10.1111/1753-0407.13107. Epub 2020 Oct 5.
Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder that usually persists into adulthood. However, limited evidence is available regarding its influence on adult health outcomes beyond neuropsychiatric comorbidities. This study aimed to examine the association of ADHD with diabetes in US adults.
We analyzed data from the National Health Interview Survey (NHIS), a leading health survey of a nationally representative sample in the United States. We included adults aged 20-79 years who participated in the NHIS 2007 and 2012. Physician-diagnosed ADHD and diabetes were reported during an in-person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratio (OR) and 95% confidence interval (CI) of diabetes.
This analysis included 52 821 adults (weighted mean age 45.5 years; 48.6% males). Among them, 1642 participants reported a diagnosis of ADHD and 4631 reported a diagnosis of diabetes. In the multivariable analysis adjusting for age, sex, race/ethnicity, education level, family income level, smoking, alcohol drinking, physical activity, and body mass index, the OR of diabetes among adults with ADHD vs those without ADHD was 1.54 (95% CI, 1.16-2.04). In the stratified analyses, the significant association of ADHD with diabetes remained in most strata, and the associations were not significantly modified by age, sex, race/ethnicity, or obesity status.
In a nationally representative sample of US adults, we found a significant association between a history of ADHD diagnosis and diabetes.
注意力缺陷多动障碍（ADHD）是一种儿童期起病的神经发育障碍，通常持续到成年期。然而，关于 ADHD 对成年期健康结果的影响，除了神经精神合并症之外，证据有限。本研究旨在检查 ADHD 与美国成年人糖尿病之间的关联。
我们分析了美国国家健康访谈调查（NHIS）的数据，这是一项针对美国全国代表性样本的主要健康调查。我们纳入了 2007 年和 2012 年参加 NHIS 的年龄在 20-79 岁的成年人。在面对面的家庭访谈中报告了医生诊断的 ADHD 和糖尿病。使用具有调查抽样权重的 logistic 回归来估计糖尿病的比值比（OR）和 95%置信区间（CI）。
这项分析包括 52821 名成年人（加权平均年龄为 45.5 岁；48.6%为男性）。其中，1642 名参与者报告了 ADHD 的诊断，4631 名参与者报告了糖尿病的诊断。在调整年龄、性别、种族/民族、教育水平、家庭收入水平、吸烟、饮酒、身体活动和体重指数后，ADHD 成年人与无 ADHD 成年人相比，糖尿病的 OR 为 1.54（95%CI，1.16-2.04）。在分层分析中，ADHD 与糖尿病之间的显著关联在大多数分层中仍然存在，并且这种关联不受年龄、性别、种族/民族或肥胖状况的显著影响。
在一个具有全国代表性的美国成年人样本中，我们发现 ADHD 诊断史与糖尿病之间存在显著关联。
