State Key Laboratory of Acoustics, Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China.
State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu 610065, China.
Ultrason Sonochem. 2021 Apr;72:105439. doi: 10.1016/j.ultsonch.2020.105439. Epub 2021 Jan 8.
The motion of particles of different properties and sizes in ALF ultrasonic cavitation structure is investigated experimentally with high-speed photography. Particles tend to transport along the bubble chain and move towards the focus repeatedly and predictably in ALF cavitation structures. Particles at the focus aggregate and separate alternately over time. The separation of particles mainly occurs in the expansion process of cavitation bubbles, while the movement and aggregation of particles mostly take place during the collapse stage. The directional transport of particles along the bubble chain of ALF cavitation cloud and the random aggregation and dispersion at the focus of ALF are all related to the cavitation bubbles attached to the particles. The directional transportation (predictable, repeatable and pipeline-free) and aggregation of particles in ALF cavitation clouds may be used in special occasions, for example, drug delivery and targeted therapy.
采用高速摄影实验研究了不同性质和尺寸的颗粒在声流空化结构中的运动。在声流空化结构中，颗粒趋向于沿气泡链运输，并反复、可预测地向焦点移动。随着时间的推移，焦点处的颗粒会交替聚集和分离。颗粒的分离主要发生在空化气泡的膨胀过程中，而颗粒的运动和聚集主要发生在空化气泡的坍塌阶段。颗粒沿着声流空化云的气泡链的定向输运以及在声流空化云的焦点处的随机聚集和弥散，都与附着在颗粒上的空化气泡有关。在声流空化云中，颗粒的定向输运（可预测、可重复且无需管道）和聚集可能会在特殊场合得到应用，例如药物输送和靶向治疗。
