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亲水性微孔聚氨酯与膨体聚四氟乙烯移植物在犬颈动脉替代中的应用:一项局限性研究。

Hydrophilic microporous polyurethane versus expanded PTFE grafts as substitutes in the carotid arteries of dogs. A limited study.

作者信息

Martz H, Paynter R, Ben Slimane S, Beaudoin G, Guidoin R, Borzone J, Ben Simhon H, Satin R, Sheiner N

机构信息

Laboratory of Experimental Surgery, Laval University, Quebec City, Canada.

出版信息

J Biomed Mater Res. 1988 Jan;22(1):63-9. doi: 10.1002/jbm.820220107.

Abstract

A novel, microporous, hydrophilic polyether urethane-urea (PEUU) vascular graft was compared with expanded PTFE in the canine carotid artery. At implantation times ranging from 4 h to 6 months, all the PEUU grafts were found to be occluded while of the PTFE grafts, only those implanted for 1 week and 6 months were blocked. Histopathological analysis of the explanted grafts and their capsules revealed an ongoing inflammatory reaction at the anastomotic sites of the PEUU grafts.

摘要

一种新型的微孔亲水性聚醚聚氨酯-脲(PEUU)血管移植物与膨体聚四氟乙烯(PTFE)在犬颈动脉中进行了比较。在植入时间从4小时到6个月的范围内,发现所有的PEUU移植物均发生闭塞,而PTFE移植物中,只有植入1周和6个月的那些发生了堵塞。对取出的移植物及其包膜进行的组织病理学分析显示,PEUU移植物吻合部位存在持续的炎症反应。

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