Martz H, Paynter R, Ben Slimane S, Beaudoin G, Guidoin R, Borzone J, Ben Simhon H, Satin R, Sheiner N
Laboratory of Experimental Surgery, Laval University, Quebec City, Canada.
J Biomed Mater Res. 1988 Jan;22(1):63-9. doi: 10.1002/jbm.820220107.
A novel, microporous, hydrophilic polyether urethane-urea (PEUU) vascular graft was compared with expanded PTFE in the canine carotid artery. At implantation times ranging from 4 h to 6 months, all the PEUU grafts were found to be occluded while of the PTFE grafts, only those implanted for 1 week and 6 months were blocked. Histopathological analysis of the explanted grafts and their capsules revealed an ongoing inflammatory reaction at the anastomotic sites of the PEUU grafts.
一种新型的微孔亲水性聚醚聚氨酯-脲(PEUU)血管移植物与膨体聚四氟乙烯(PTFE)在犬颈动脉中进行了比较。在植入时间从4小时到6个月的范围内,发现所有的PEUU移植物均发生闭塞,而PTFE移植物中,只有植入1周和6个月的那些发生了堵塞。对取出的移植物及其包膜进行的组织病理学分析显示,PEUU移植物吻合部位存在持续的炎症反应。