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表现出明显黏液细胞化生的含牙囊肿:一例独特病例报告,该病例模仿中央黏液表皮样癌。

Dentigerous cyst exhibiting prominent mucous cell metaplasia: report of a unique case mimicking central mucoepidermoid carcinoma.

机构信息

Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, 5 Zaifu, Hirosaki, 036-8562, Japan.

Kihara Dental Clinic, Ogohri, Japan.

出版信息

Med Mol Morphol. 2021 Sep;54(3):253-258. doi: 10.1007/s00795-020-00278-y. Epub 2021 Jan 12.

DOI:10.1007/s00795-020-00278-y
PMID:33433728
Abstract

A Japanese male aged 61 presented with persistent pain in the left posterior area of the mandible for several weeks. A panoramic X-ray revealed a unilocular lesion showing characteristics of a dentigerous cyst associated with an impacted third molar. A cystectomy was performed and histopathological examination revealed a cystic lesion with a fibrous wall. The lumen was covered with non-keratinizing squamous cells with obvious intercellular bridges, which were intermingled with partially ciliated goblet-cell-type mucous and columnar cells. Such cystic lesions should be carefully examined to distinguish them from the glandular odontogenic cyst and central mucoepidermoid carcinoma of the jawbone.

摘要

一位 61 岁的日本男性出现左下颚后部持续性疼痛数周。全景 X 光片显示单侧病变,具有与阻生第三磨牙相关的含牙囊肿特征。进行了囊肿切除术,组织病理学检查显示囊腔病变伴纤维壁。腔隙被覆非角化复层鳞状细胞,有明显的细胞间桥,间杂有部分纤毛杯状细胞型黏液和柱状细胞。此类囊性病变应仔细检查,以与颌骨的腺牙源性囊肿和中央黏液表皮样癌相鉴别。

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本文引用的文献

1
MAML2 rearrangement in primary pulmonary mucoepidermoid carcinoma and the correlation with FLT1 expression.原发性肺黏液表皮样癌中MAML2重排及其与FLT1表达的相关性
PLoS One. 2014 Apr 8;9(4):e94399. doi: 10.1371/journal.pone.0094399. eCollection 2014.
2
The MUC gene family: their role in the diagnosis and prognosis of gastric cancer.MUC基因家族:它们在胃癌诊断和预后中的作用。
Histol Histopathol. 2008 Dec;23(12):1541-52. doi: 10.14670/HH-23.1541.