Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, 5 Zaifu, Hirosaki, 036-8562, Japan.
Kihara Dental Clinic, Ogohri, Japan.
Med Mol Morphol. 2021 Sep;54(3):253-258. doi: 10.1007/s00795-020-00278-y. Epub 2021 Jan 12.
A Japanese male aged 61 presented with persistent pain in the left posterior area of the mandible for several weeks. A panoramic X-ray revealed a unilocular lesion showing characteristics of a dentigerous cyst associated with an impacted third molar. A cystectomy was performed and histopathological examination revealed a cystic lesion with a fibrous wall. The lumen was covered with non-keratinizing squamous cells with obvious intercellular bridges, which were intermingled with partially ciliated goblet-cell-type mucous and columnar cells. Such cystic lesions should be carefully examined to distinguish them from the glandular odontogenic cyst and central mucoepidermoid carcinoma of the jawbone.
一位 61 岁的日本男性出现左下颚后部持续性疼痛数周。全景 X 光片显示单侧病变,具有与阻生第三磨牙相关的含牙囊肿特征。进行了囊肿切除术,组织病理学检查显示囊腔病变伴纤维壁。腔隙被覆非角化复层鳞状细胞,有明显的细胞间桥,间杂有部分纤毛杯状细胞型黏液和柱状细胞。此类囊性病变应仔细检查,以与颌骨的腺牙源性囊肿和中央黏液表皮样癌相鉴别。