Barnard N J, George B D, Tucker A K, Gilmore O J
Department of Pathology, St Bartholomew's Hospital, London.
J Clin Pathol. 1988 Jan;41(1):26-30. doi: 10.1136/jcp.41.1.26.
Over four years the histological features of benign breast diseases, diagnosed after biopsy of non-palpable mammographic abnormalities, were reviewed and correlated with the mammographic appearances. The histological features were compared with those from all other benign biopsy specimens taken during the same period. The incidence of sclerosing adenosis and microcalcifications was considerably higher in the group of non-palpable mammographic lesions; fibrous disease of the breast and radial scar (infiltrating epitheliosis) were also more common. There was no difference in the incidence of epithelial hyperplasia between the two groups. Correlation with the mammographic appearances showed that microcalcification was most often associated with blunt duct adenosis and that stromal distortion or masses were most often caused by fibrous disease.
在四年时间里，对经活检诊断为乳腺良性疾病的、乳腺钼靶检查发现的触诊阴性异常的组织学特征进行了回顾，并与乳腺钼靶表现相关联。将这些组织学特征与同期获取的所有其他良性活检标本的特征进行了比较。在乳腺钼靶触诊阴性病变组中，硬化性腺病和微钙化的发生率明显更高；乳腺纤维病和放射状瘢痕（浸润性上皮增生）也更常见。两组之间上皮增生的发生率没有差异。与乳腺钼靶表现的关联显示，微钙化最常与钝圆导管腺病相关，而间质变形或肿块最常由纤维病引起。
