Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
Atlantic Fellow for Equity in Brain Health at UCSF and clinical researcher Instituto Nacional de Ciencias Neurológicas (INCN), Lima, Peru.
Adv Exp Med Biol. 2021;1281:17-31. doi: 10.1007/978-3-030-51140-1_2.
Behavioral variant frontotemporal dementia (bvFTD) is a syndrome defined by a set of core clinical criteria, which include disinhibition; apathy or inertia; loss of sympathy or empathy; perseverative, stereotyped, or compulsive/ritualistic behavior; and hyperorality. The clinical features of bvFTD overlap substantially with those of psychiatric disease, particularly major depressive disorder and bipolar affective disorder. The similarities between bvFTD and primary psychiatric disease results in a significant diagnostic challenge for clinicians. Understanding the neuropsychiatric aspects of bvFTD may assist in differentiating bvFTD from a primary psychiatric disorder.
行为变异型额颞叶痴呆（bvFTD）是一种综合征，由一组核心临床标准定义，包括：抑制障碍；淡漠或无动力；同情心或同理心丧失；持续、刻板或强迫/仪式性行为；以及过度进食。bvFTD 的临床特征与精神疾病，特别是重度抑郁症和双相情感障碍，有很大的重叠。bvFTD 与原发性精神疾病之间的相似性给临床医生带来了重大的诊断挑战。了解 bvFTD 的神经精神方面可能有助于将其与原发性精神障碍区分开来。
