• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肉毒毒素作为一种治疗耳颞神经痛的新方法。

Botulinum toxin as a novel therapeutic approach for auriculotemporal neuralgia.

机构信息

Department of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.

Department of Clinical Neurosciences and Mental Health, Faculty of Medicine of University of Porto, Porto, Portugal.

出版信息

Headache. 2021 Feb;61(2):392-395. doi: 10.1111/head.14043. Epub 2021 Jan 12.

DOI:10.1111/head.14043
PMID:33433917
Abstract

OBJECTIVES/BACKGROUND: Auriculotemporal neuralgia is a rare headache disorder. Anesthetic nerve blockade seems to be effective in most cases; however, literature is scarce about the management of refractory cases.

METHODS

Case report.

RESULTS

We report a 44-year-old woman with migraine without aura presented with moderate-to-severe right temporoparietal headache. The pain was refractory to multiple pharmacological strategies, including intravenous analgesia. A more throughout examination lead to the diagnosis of auriculotemporal neuralgia and anesthetic nerve blocks were performed. Due to early pain recrudescence, botulinum toxin (BoNT) was tried with better and longstanding pain control.

CONCLUSION

BoNT may be a useful treatment option in refractory auriculotemporal neuralgia. The best approach is yet to be established; however, the "follow-the-pain" protocol may be a reasonable option.

摘要

目的/背景:耳颞神经痛是一种罕见的头痛疾病。麻醉神经阻滞似乎对大多数病例有效;然而,关于难治性病例的治疗方法文献较少。

方法

病例报告。

结果

我们报告了一例 44 岁女性,偏头痛不伴先兆,表现为中度至重度右颞顶头痛。疼痛对多种药物治疗策略(包括静脉内镇痛)均有抵抗。更全面的检查导致诊断为耳颞神经痛,并进行了麻醉神经阻滞。由于早期疼痛复发,尝试使用肉毒毒素(BoNT),疼痛得到了更好和持久的控制。

结论

BoNT 可能是难治性耳颞神经痛的一种有效治疗选择。最佳方法尚待确定;然而,“跟随疼痛”的方案可能是一个合理的选择。

相似文献

1
Botulinum toxin as a novel therapeutic approach for auriculotemporal neuralgia.肉毒毒素作为一种治疗耳颞神经痛的新方法。
Headache. 2021 Feb;61(2):392-395. doi: 10.1111/head.14043. Epub 2021 Jan 12.
2
Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia-A Case Series.A型肉毒毒素治疗耳颞神经痛-病例系列。
Toxins (Basel). 2023 Apr 6;15(4):274. doi: 10.3390/toxins15040274.
3
Therapeutic success with local botulinum toxin in erythromelalgia.局部注射肉毒杆菌毒素治疗红斑性肢痛症取得成功。
Pain Physician. 2014 Sep-Oct;17(5):E658-60.
4
Botulinum toxin occipital nerve block for the treatment of severe occipital neuralgia: a case series.肉毒杆菌毒素枕神经阻滞治疗重度枕神经痛:病例系列
Pain Pract. 2007 Dec;7(4):337-40. doi: 10.1111/j.1533-2500.2007.00150.x. Epub 2007 Nov 6.
5
Safety and efficacy of repeated injections of botulinum toxin A in peripheral neuropathic pain (BOTNEP): a randomised, double-blind, placebo-controlled trial.A型肉毒毒素反复注射治疗周围神经病理性疼痛的安全性和有效性(BOTNEP):一项随机、双盲、安慰剂对照试验。
Lancet Neurol. 2016 May;15(6):555-65. doi: 10.1016/S1474-4422(16)00017-X. Epub 2016 Mar 2.
6
Pulsed Radiofrequency for Auriculotemporal Neuralgia: A Case Report.脉冲射频治疗耳颞神经痛:一例报告
Neurol Int. 2024 Mar 12;16(2):349-355. doi: 10.3390/neurolint16020025.
7
Botulinum Toxin Type-A (Botulax) Treatment in Patients with Intractable Chronic Occipital Neuralgia: A Pilot Study.A型肉毒毒素(保妥适)治疗难治性慢性枕神经痛患者:一项初步研究。
Toxins (Basel). 2021 May 4;13(5):332. doi: 10.3390/toxins13050332.
8
Subcutaneous botulinum toxin for chronic post-thoracotomy pain.皮下注射肉毒毒素治疗慢性开胸术后疼痛。
Pain Pract. 2013 Mar;13(3):231-4. doi: 10.1111/j.1533-2500.2012.00569.x. Epub 2012 Jun 21.
9
A new target for the treatment of trigeminal neuralgia with botulinum toxin type A.A型肉毒毒素治疗三叉神经痛的新靶点。
Neurol Sci. 2018 Mar;39(3):599-602. doi: 10.1007/s10072-017-3171-7. Epub 2017 Oct 30.
10
Ultrasound-Guided Nerve Block with Botulinum Toxin Type A for Intractable Neuropathic Pain.超声引导下A型肉毒杆菌毒素神经阻滞治疗顽固性神经性疼痛
Toxins (Basel). 2016 Jan 8;8(1):18. doi: 10.3390/toxins8010018.

引用本文的文献

1
Pulsed Radiofrequency for Auriculotemporal Neuralgia: A Case Report.脉冲射频治疗耳颞神经痛:一例报告
Neurol Int. 2024 Mar 12;16(2):349-355. doi: 10.3390/neurolint16020025.
2
A rare case of the auriculotemporal and inferior alveolar nerves communication.一例罕见的耳颞神经和下牙槽神经交通。
Surg Radiol Anat. 2024 Feb;46(2):191-194. doi: 10.1007/s00276-023-03283-9. Epub 2023 Dec 27.
3
Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia-A Case Series.A型肉毒毒素治疗耳颞神经痛-病例系列。
Toxins (Basel). 2023 Apr 6;15(4):274. doi: 10.3390/toxins15040274.
4
Associations between Zygoma Fracture and Post-Traumatic Headache: A Study among Taiwanese Population.颧骨骨折与创伤后头痛之间的关联:一项针对台湾人群的研究。
J Clin Med. 2021 Nov 18;10(22):5377. doi: 10.3390/jcm10225377.