Hsiao I-Han, Hsu Shao-Yun, Lin Mei-Chen, Shih Pin-Keng
Department of Neurosurgery, China Medical University Hospital, Taichung 404, Taiwan.
Graduate Institute of Acupuncture Science, China Medical University, Taichung 404, Taiwan.
J Clin Med. 2021 Nov 18;10(22):5377. doi: 10.3390/jcm10225377.
Few studies have discussed the development of post-traumatic headache (PTH) after zygoma fracture. This research aimed to examine the association between zygoma fracture and PTH and its other associated factors. A total of 3043 patients with zygoma fracture and 3043 patients with non-fracture were included in this analysis. They were matched to a non-fracture cohort from the National Health Insurance database according to age, sex, and index year. The incidence of PTH and its association with zygoma fracture were assessed. The zygoma fracture cohort had a significantly higher cumulative incidence of PTH than the non-fracture cohort in a 10-year follow-up. The confounding risk factors of PTH included zygoma fracture, female sex, and comorbidities, including obesity and depression. Female patients under 40 years old who had zygoma fractures had a higher incidence of PTH than the non-fracture group. Moreover, patients with zygoma fractures commonly developed PTH within three months after injury. Female patients under 40 years old with precedent zygoma fractures had a higher incidence rate of PTH than those without fractures. Moreover, patients with zygoma fractures commonly developed PTH within three months after injury. Nevertheless, before widely applying our results, a prospective study must be conducted to verify the risk factors found in this study.
很少有研究讨论颧骨骨折后创伤后头痛（PTH）的发生情况。本研究旨在探讨颧骨骨折与PTH之间的关联及其其他相关因素。本分析共纳入3043例颧骨骨折患者和3043例非骨折患者。根据年龄、性别和索引年份，将他们与来自国民健康保险数据库的非骨折队列进行匹配。评估了PTH的发生率及其与颧骨骨折的关联。在10年的随访中，颧骨骨折队列的PTH累积发生率显著高于非骨折队列。PTH的混杂风险因素包括颧骨骨折、女性性别以及合并症，包括肥胖和抑郁症。40岁以下发生颧骨骨折的女性患者PTH发生率高于非骨折组。此外，颧骨骨折患者通常在受伤后三个月内发生PTH。40岁以下有既往颧骨骨折的女性患者PTH发生率高于无骨折者。此外，颧骨骨折患者通常在受伤后三个月内发生PTH。然而，在广泛应用我们的结果之前，必须进行前瞻性研究以验证本研究中发现的风险因素。
