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NCI-MATCH:一项针对多种肿瘤组织学类型的全国性协作精准肿瘤学试验。

The NCI-MATCH: A National, Collaborative Precision Oncology Trial for Diverse Tumor Histologies.

作者信息

Murciano-Goroff Yonina R, Drilon Alexander, Stadler Zsofia K

机构信息

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA.

出版信息

Cancer Cell. 2021 Jan 11;39(1):22-24. doi: 10.1016/j.ccell.2020.12.021.

Abstract

The NCI-MATCH is a national master protocol trial, published in the Journal of Clinical Oncology, in which diverse tumors are sequenced and patients assigned to treatment. The trial demonstrates the feasibility of identifying rare and common actionable genetic alterations and underscores the strength of academic/community partnerships for improving trial access.

摘要

NCI-MATCH是一项发表于《临床肿瘤学杂志》的全国性主方案试验,其中对多种肿瘤进行测序,并为患者分配治疗方案。该试验证明了识别罕见和常见可操作基因改变的可行性,并强调了学术/社区伙伴关系在改善试验准入方面的优势。

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