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糖尿病在不同世代间存在差异吗?荷兰三代摩鹿加人。

Do Diabetes Mellitus Differences Exist within Generations? Three Generations of Moluccans in the Netherlands.

机构信息

Department of Public and Occupational Health, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

出版信息

Int J Environ Res Public Health. 2021 Jan 9;18(2):493. doi: 10.3390/ijerph18020493.

DOI:10.3390/ijerph18020493
PMID:33435344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7827698/
Abstract

Diabetes mellitus (DM) is known to be more prevalent among migrants compared to their host populations. It is unclear whether DM prevalence differs between generations among migrants. We investigated the differences in DM prevalence among three generations of Moluccans, who have been living for over 65 years in the Netherlands, compared to the Dutch population. : In this cross-sectional study, data of a healthcare insurance database on hospital and medication use (Achmea Health Database) were used. The dataset contained 5394 Moluccans and 52,880 Dutch persons of all ages. DM differences were assessed by means of logistic regression, adjusting for age, sex, urbanization, and area socio-economic status. : The prevalence of DM was higher in all generations of Moluccans compared to the Dutch. The adjusted odds ratios (AORs) for DM were significantly higher in total group of Moluccans compared to the Dutch (AOR 1.60, 95% CI 1.42-1.80) and across the first and second generation of Moluccans compared to the Dutch (first generation (1.73, 1.47-2.04) and second generation (1.44, 1.19-1.75). Higher AOR were found for first generation men (1.55, 1.22-1.97) and first (1.90, 1.52-2.37) and second (1.63, 1.24-2.13) generation Moluccan women compared to the Dutch. AOR for the third generation Moluccans was increased to a similar extent (1.51, 0.97-2.34), although not statistical significant. : Our findings show higher odds of DM across generations of Moluccans compared to the Dutch. DM prevention strategies for minorities should be targeted at all migrant generations in host countries.

摘要

糖尿病(DM)在移民中比在其宿主人群中更为普遍。目前尚不清楚移民中各代之间的 DM 患病率是否存在差异。我们调查了在荷兰生活了 65 年以上的三代摩鹿加人(Moluccans)与荷兰人口之间 DM 患病率的差异。

在这项横断面研究中,使用了医疗保险数据库中关于医院和药物使用的(Achmea 健康数据库)的数据。该数据集包含 5394 名摩鹿加人和 52880 名荷兰各年龄段的人。通过逻辑回归评估 DM 差异,调整年龄、性别、城市化和地区社会经济状况。

所有代摩鹿加人的 DM 患病率均高于荷兰人。与荷兰人相比,摩鹿加人总体(调整后的优势比 [AOR] 1.60,95%置信区间 [CI] 1.42-1.80)和第一代和第二代摩鹿加人(第一代(1.73,1.47-2.04)和第二代(1.44,1.19-1.75)的 DM 调整后的优势比明显更高。第一代男性(1.55,1.22-1.97)和第一代(1.90,1.52-2.37)和第二代(1.63,1.24-2.13)的摩鹿加女性的 AOR 更高。尽管没有统计学意义,但第三代摩鹿加人的 AOR 增加到类似程度(1.51,0.97-2.34)。

我们的研究结果表明,与荷兰人相比,摩鹿加人各代的 DM 患病率更高。在东道国,针对少数民族的 DM 预防策略应针对所有移民代际。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdc9/7827698/0d1c2609c209/ijerph-18-00493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdc9/7827698/0d1c2609c209/ijerph-18-00493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdc9/7827698/0d1c2609c209/ijerph-18-00493-g001.jpg

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