Suppr超能文献

新型冠状病毒肺炎危重症患者高血糖的重要性:机制与治疗策略。

Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy.

机构信息

Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Department of Anatomical Sciences, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Prim Care Diabetes. 2021 Jun;15(3):409-416. doi: 10.1016/j.pcd.2021.01.002. Epub 2021 Jan 9.

Abstract

This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, induce apoptosis, and reduce antioxidant in the lungs. We provide a possible mechanism in severe COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes after intensive care unit (ICU).

摘要

这篇综述报道称,感染 2019 冠状病毒病(COVID-19)的患者在短时间卧床休息或隔离期间以及气道炎症时,更易发生高血糖和胰岛素抵抗。这种情况会导致氧化应激,降低免疫系统功能,损害内皮功能,诱导细胞凋亡,并减少肺部的抗氧化剂。我们提供了严重 COVID-19 患者的一种可能机制,并建议了治疗策略,以降低重症监护病房(ICU)后的死亡率和预防不良后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ab6/7834268/2223c332563f/gr1_lrg.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验