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扩张器假体与 DIEP 皮瓣在乳房重建中的短期比较:一项前瞻性随机研究。

A short-term comparison of expander prosthesis and DIEP flap in breast reconstructions: A prospective randomized study.

机构信息

Skåne University Hospital, Department of Plastic and Reconstructive Surgery, Jan Waldenströms gata 18, 20501 Malmö, Sweden.

Skåne University Hospital, Department of Plastic and Reconstructive Surgery, Jan Waldenströms gata 18, 20501 Malmö, Sweden.

出版信息

J Plast Reconstr Aesthet Surg. 2021 Jun;74(6):1193-1202. doi: 10.1016/j.bjps.2020.10.104. Epub 2020 Nov 12.

DOI:10.1016/j.bjps.2020.10.104
PMID:33436336
Abstract

BACKGROUND

There is yet no clear consensus on which method is preferable in secondary breast reconstructions, prosthesis, or autologous tissue.

METHODS

In this first prospective randomized study, 29 women underwent reconstruction with expander prosthesis (EP) and 44 with deep inferior epigastric perforator (DIEP) flap. Inclusion started in 2012 and ended in 2018. Demographic data, complications, surgery time, hospital days, and consulting visits were recorded. Patient satisfaction was evaluated pre- and postoperatively using the BREAST-Q questionnaire. Health care costs were calculated based on rates from the financial year 2018. Here, we report the results related to the surgery and the first 30 postoperative days.

RESULTS

The two groups were comparable regarding demographics and clinical characteristics. Satisfaction with breasts, measured with BREAST-Q, was significantly higher in patients who had undergone reconstruction with DIEP flap compared with EP. Within 30 days after breast reconstruction, significantly fewer women (n = 2) in the EP group suffered complications compared to the DIEP flap group (n = 16; p < 0.01). The health care cost was also significantly higher in the DIEP flap group relative to the EP group (p < 0.01).

DISCUSSION

This patient cohort will be studied systematically over time, and results concerning the need for complementary surgery, costs, esthetics, and the patient-reported outcome (PRO) will be reported in future work. In this short-term report, EP seems to be preferable in regard to cost and complications, and DIEP flap is to choose from the patient's perspective.

摘要

背景

在继发性乳房重建中,假体或自体组织哪种方法更优尚未达成明确共识。

方法

这是第一项前瞻性随机研究,29 名女性接受了扩张器假体(EP)重建,44 名女性接受了腹壁下动脉穿支皮瓣(DIEP)重建。纳入工作于 2012 年开始,2018 年结束。记录了人口统计学数据、并发症、手术时间、住院天数和就诊次数。采用 BREAST-Q 问卷对患者术前和术后的满意度进行评估。根据 2018 财年的费率计算医疗保健费用。本文报告了与手术和术后 30 天相关的结果。

结果

两组在人口统计学和临床特征方面具有可比性。采用 BREAST-Q 测量的乳房满意度,DIEP 皮瓣重建组显著高于 EP 组。在乳房重建后 30 天内,EP 组并发症的女性(n=2)明显少于 DIEP 皮瓣组(n=16;p<0.01)。DIEP 皮瓣组的医疗保健费用也明显高于 EP 组(p<0.01)。

讨论

本患者队列将随着时间的推移进行系统研究,未来的工作中将报告关于补充手术的需求、成本、美容效果和患者报告的结果(PRO)的结果。在这项短期报告中,EP 在成本和并发症方面似乎更具优势,而 DIEP 皮瓣则更受患者选择。

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