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内脏动脉巨大动脉瘤的血管内治疗。

Endovascular management of giant visceral artery aneurysms.

机构信息

Department of Radiology, Sant' Andrea University Hospital La Sapienza, Rome, Italy.

Department of Surgical and Medical Sciences and Translational Medicine, School of Medicine and Psychology, "Sapienza", University of Rome, Rome, Italy.

出版信息

Sci Rep. 2021 Jan 12;11(1):700. doi: 10.1038/s41598-020-80150-2.

Abstract

Endovascular management of small visceral artery aneurysms is an established treatment with satisfactory outcomes. However, when size exceeds 5 cm visceral aneurysms are considered as "giant" (giant visceral artery aneurysms or GVAAs) and management is significantly more complex. Between August 2007 and June 2019 eleven cases of GVAAs that were endovascularly treated were retrospectively reviewed and included in this single center study. Mean size was 80 mm (± 26.3 mm) x 46 mm (+ -11.8 mm). Nine of the lesions were true aneurysms, and two were pseudoaneurysms. In 8 patients, the lesion was causing compression symptoms in the surrounding organs, one patient developed a contained rupture while 2 patients were completely asymptomatic. However, all patients were hemodynamically stable at the time of treatment. Technical success was defined as immediate complete exclusion of the aneurysmal sac, and clinical success as complete relief from clinical symptoms. Follow-up was performed with CT angiography, ultrasound and clinical examination. Mean follow-up was 45 months (range 6-84). Technical and clinical success were both 91%. Complications were one lack of control of contained rupture that was subsequently operated, one case of self-limiting non-target spleen embolization and one case of splenic abscess. Three patients died, one due to the contained rupture 15 days after procedure, the other two for other causes and occurred during the long-term follow-up. This series suggests that endovascular treatment of giant visceral artery aneurysms and pseudoaneuryms is a valid minimally invasive solution with very satisfactory immediate and long-term outcomes unless the aneurysm is already ruptured. A variety of endovascular tools may be required for successful treatment.

摘要

腔内治疗小型内脏动脉动脉瘤已被确立为一种有效的治疗方法,其疗效令人满意。然而,当动脉瘤的直径超过 5cm 时,就被认为是“巨大”的(巨大内脏动脉动脉瘤或 GVAAs),其治疗就变得更加复杂。在 2007 年 8 月至 2019 年 6 月期间,我们回顾性地研究了 11 例接受腔内治疗的 GVAAs,并将这些病例纳入了这项单中心研究。平均直径为 80mm(+/-26.3mm)×46mm(+/-11.8mm)。9 个病变为真性动脉瘤,2 个为假性动脉瘤。在 8 例患者中,病变对周围器官有压迫症状,1 例发生隐匿性破裂,2 例患者无症状。然而,所有患者在治疗时血流动力学均稳定。技术成功定义为即刻完全排除动脉瘤囊,临床成功定义为完全缓解临床症状。通过 CT 血管造影、超声和临床检查进行随访。平均随访时间为 45 个月(6-84 个月)。技术成功率和临床成功率均为 91%。并发症包括 1 例隐匿性破裂未得到控制,随后进行了手术治疗,1 例脾栓塞为非目标性且自行缓解,1 例脾脓肿。3 例患者死亡,1 例在手术后 15 天因隐匿性破裂死亡,另外 2 例死于其他原因,均发生在长期随访期间。本研究表明,除非动脉瘤已经破裂,否则腔内治疗巨大内脏动脉动脉瘤和假性动脉瘤是一种有效的微创治疗方法,其即刻和长期疗效非常令人满意。可能需要各种腔内治疗工具来获得成功的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73e/7803780/dad9b7f24132/41598_2020_80150_Fig1_HTML.jpg

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