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覆膜支架治疗内脏动脉瘤患者的超长期CT血管造影评估:单中心病例系列

Ultra-Long-Term CT Angiography Evaluation of Patients Treated with Covered Stents for Visceral Aneurysms: A Single Center Case Series.

作者信息

Tipaldi Marcello Andrea, Ubaldi Nicolò, Ronconi Edoardo, Ortenzi Michela, Arbia Francesco, Orgera Gianluigi, Krokidis Miltiadis, Rossi Tommaso, Sirignano Pasqualino, Rizzo Luigi, Rossi Michele

机构信息

Interventional Radiology Unit, Department of Surgical and Medical Sciences and Translational Medicine, Sant'Andrea Hospital of Rome, "Sapienza" University of Rome, 00189 Rome, Italy.

School of Medicine, Areteion Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.

出版信息

Diagnostics (Basel). 2025 Jun 11;15(12):1481. doi: 10.3390/diagnostics15121481.

Abstract

Endovascular repair of visceral artery aneurysms (VAAs) and visceral artery pseudoaneurysms (VAPAs) using covered stent grafts is a novel technique that preserves efferent vessel patency and prevents end-organ ischemia; however, long-term results are lacking in the literature. This study aims to evaluate ultra-long-term outcomes (>5 years) using CT angiography (CTA) and technical aspects of covered stents in treating VAAs and VAPAs. A single-center retrospective study was conducted on patients with VAAs and VAPAs treated with stent grafts between 2004 and 2023. The study included an ultra-long-term follow-up using CTA. Stent graft patency, aneurysm characteristics, technical success, 30-day and long-term follow-up clinical success, and mortality were assessed. Among 23 patients presenting with VAAs and VAPAs treated exclusively with covered stents implantation, 7 (mean age: 68 years, SD 14), including 5 with VAAs and 2 with VAPAs, met the inclusion criteria for the study. Six of the seven patients underwent elective procedures with no significant periprocedural complications. Both technical and 30-day clinical success rates were 100%. The mean follow-up period was 10 years (125 months SD 53). At the 5-year follow-up, 71% of stent grafts remained patent. No patient experienced aneurysm sac revascularization or rupture. Stent obstruction did not affect survival. This study demonstrates that endovascular covered stenting is a durable and effective treatment for VAAs and VAPAs, even in the ultra-long term, with a patency rate of 71% at a mean CTA follow-up of 125 months, the longest reported to date and no cases of sac revascularization. Stent thrombosis was significantly associated with VAPAs.

摘要

使用覆膜支架移植物对内脏动脉瘤(VAA)和内脏动脉假性动脉瘤(VAPA)进行血管内修复是一种保留传出血管通畅并预防终末器官缺血的新技术;然而,文献中缺乏长期结果。本研究旨在使用CT血管造影(CTA)评估超长期(>5年)结果以及覆膜支架治疗VAA和VAPA的技术方面。对2004年至2023年间接受支架移植物治疗的VAA和VAPA患者进行了一项单中心回顾性研究。该研究包括使用CTA进行的超长期随访。评估了支架移植物通畅情况、动脉瘤特征、技术成功率、30天和长期随访临床成功率以及死亡率。在仅接受覆膜支架植入治疗的23例VAA和VAPA患者中,7例(平均年龄:68岁,标准差14)符合研究纳入标准,其中5例为VAA,2例为VAPA。7例患者中有6例接受了择期手术,围手术期无明显并发症。技术成功率和30天临床成功率均为100%。平均随访期为10年(125个月,标准差53)。在5年随访时,71%的支架移植物仍保持通畅。没有患者出现动脉瘤囊再血管化或破裂。支架阻塞不影响生存。本研究表明,血管内覆膜支架置入术即使在超长期对VAA和VAPA也是一种持久有效的治疗方法,在平均CTA随访125个月时通畅率为71%,这是迄今为止报道的最长时间,且无囊再血管化病例。支架血栓形成与VAPA显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7085/12192089/3d89eff4b774/diagnostics-15-01481-g001.jpg

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