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持续性腹泻儿童隐孢子虫病的发病率

Frequency of Cryptosporidiosis in Children having Persistent Diarrhea.

作者信息

Iqbal Mariam Danish, Naeem Tahir, Khurshid Umar, Hameed Fatima

机构信息

Mariam Danish Iqbal, FCPS Microbiology. Pathology Department, Shalamar Medical & Dental College, Lahore, Pakistan.

Tahir Naeem, MCPS, D(ABMM). Pathology Department, Shalamar Medical & Dental College, Lahore, Pakistan.

出版信息

Pak J Med Sci. 2021 Jan-Feb;37(1):121-124. doi: 10.12669/pjms.37.1.2700.

DOI:10.12669/pjms.37.1.2700
PMID:33437262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7794158/
Abstract

OBJECTIVE

Globally childhood diarrheal diseases continue to be the second leading cause of death. are important intestinal parasites that cause diarrhea in humans and animals particularly in developing countries. This investigation was carried out to find out the frequency of cryptosporidiosis in children presenting with persistent diarrhea.

METHODS

Two hundred stool samples were collected in this descriptive cross-sectional study conducted at Microbiology Department, Combined Military Hospital, Lahore Pakistan between the months of July to Dec 2014. Children aged five years to 12 years who presented with persistent diarrhea were included in the study. Stool specimens were processed using the modified acid-fast staining method, and microscopically examined for infection.

RESULTS

The average age of study participants was 7.95 with a standard deviation of 2.21 years. Among the participants 66% were males whereas 34% were females. Twenty eight percent had presence of oocysts in stool samples.

CONCLUSIONS

The frequency of Cryptosporidiosis among children with persistent diarrhea was 28%. This high frequency indicates that this population is uniquely susceptible to infection. It also highlights the need for education about hygiene, accurate diagnosis, and treatment of Cryptosporidiosis. There is also a need for additional studies regarding the occurrence of this pathogen.

摘要

目的

在全球范围内,儿童腹泻病仍然是第二大死亡原因。隐孢子虫是重要的肠道寄生虫,可导致人类和动物腹泻,在发展中国家尤为如此。本研究旨在了解持续性腹泻儿童中隐孢子虫病的感染率。

方法

本描述性横断面研究于2014年7月至12月在巴基斯坦拉合尔联合军事医院微生物科进行,收集了200份粪便样本。研究纳入了5至12岁出现持续性腹泻的儿童。粪便标本采用改良抗酸染色法处理,并在显微镜下检查隐孢子虫感染情况。

结果

研究参与者的平均年龄为7.95岁,标准差为2.21岁。参与者中66%为男性,34%为女性。28%的粪便样本中发现了卵囊。

结论

持续性腹泻儿童中隐孢子虫病的感染率为28%。如此高的感染率表明该人群对感染具有独特的易感性。这也凸显了开展卫生教育、准确诊断和治疗隐孢子虫病的必要性。此外,还需要对该病原体的发生情况进行更多研究。

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本文引用的文献

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Cryptosporidiosis in Children in Duhok City / Kurdistan Region / Iraq.伊拉克库尔德地区杜胡克市儿童隐孢子虫病
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Infection: Epidemiology, Pathogenesis, and Differential Diagnosis.感染:流行病学、发病机制与鉴别诊断
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Prevalence and risk factors associated with cryptosporidiosis among children within the ages 0-5 years attending the Limbe regional hospital, southwest region, Cameroon.喀麦隆西南大区利姆贝地区医院 0-5 岁儿童中隐孢子虫病的流行情况及相关危险因素。
BMC Public Health. 2019 Aug 20;19(1):1144. doi: 10.1186/s12889-019-7484-8.
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Evaluation of prevalence and risk factors associated with Cryptosporidium infection in rural population of district Buner, Pakistan.评价巴基斯坦布纳尔地区农村人口中隐孢子虫感染的流行情况和相关危险因素。
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An extensive burden of giardiasis associated with intestinal schistosomiasis and anaemia in school children on the shoreline of Lake Albert, Uganda.乌干达艾伯特湖沿岸学童中,贾第虫病与肠道血吸虫病及贫血相关的负担广泛。
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Ruling out nosocomial transmission of Cryptosporidium in a renal transplantation unit: case report.排除肾移植病房隐孢子虫的医院内传播:病例报告
BMC Infect Dis. 2016 Aug 2;16:363. doi: 10.1186/s12879-016-1661-5.
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Environmental Enteric Dysfunction in Children.儿童环境性肠道功能障碍
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Identification of opportunistic enteric parasites among immunocompetent patients with diarrhoea from Northern India and genetic characterisation of Cryptosporidium and Microsporidia.印度北部腹泻免疫功能正常患者中机会性肠道寄生虫的鉴定以及隐孢子虫和微孢子虫的基因特征分析
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Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia.针对引起腹泻的小肠主要寄生虫隐孢子虫和贾第鞭毛虫的药物研发
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