Tamomh Abdelhakam G, Agena AbdElhadi M, Elamin Elham, Suliman Mohammed A, Elmadani Mohammed, Omara Asmaa B, Musa Sahar A
Department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, 27711, Kosti, Sudan.
Department of Haematology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, 27711, Kosti, Sudan.
BMC Infect Dis. 2021 Apr 14;21(1):349. doi: 10.1186/s12879-021-06047-1.
Cryptosporidiosis is a disease caused by infection with an intestinal coccidian parasite Cryptosporidium. Cryptosporidium species are the second leading cause of diarrheal disease and death in children in developing countries. Until now, no data have been available or published on its prevalence among children with diarrhea in Sudan. Therefore, this paper was designed to determine the prevalence rate of Cryptosporidium among children with diarrhea under 5 years who were admitted to Kosti Teaching Hospital.
A hospital-based cross-sectional study including children under 5 years old admitted to the pediatric section of the hospital between September 2020 and December 2020. A total of one-hundred and fifty stool samples were collected. All stool samples were examined using the modified Ziehl Neelsen (mZN) staining technique and then examined microscopically for Cryptosporidium infection.
A total of 150 children were examined out of which 70 presented with diarrhea. A greater prevalence of 19/70 (27.1%) of Cryptosporidium was observed in children with diarrhea than children without diarrhea 7/80 (8.8%). There was a significant relationship between the prevalence of Cryptosporidium and the presence of diarrhea in children under 5 years in the Kosti Teaching Hospital(P < 0.05). It was found that a higher prevalence was registered among children using piped-water sources for drinking.
The overall prevalence of parasite detected was 17.3% among children admitted to Kosti Teaching Hospital. The prevalence rate of the infection among Children with diarrhoea was 27.1%. Studying the prevalence rate of cryptosporidiosis among diarrheic children may predict their health status, leading to a better diagnosis, treatment, and, therefore, patients' status improvement.
隐孢子虫病是一种由肠道球虫寄生虫隐孢子虫感染引起的疾病。隐孢子虫种类是发展中国家儿童腹泻病和死亡的第二大主要原因。到目前为止，苏丹腹泻儿童中其流行情况尚无可用或已发表的数据。因此，本文旨在确定入住科斯蒂教学医院的5岁以下腹泻儿童中隐孢子虫的流行率。
一项基于医院的横断面研究，纳入2020年9月至2020年12月期间入住该医院儿科的5岁以下儿童。共收集了150份粪便样本。所有粪便样本均采用改良齐-尼（mZN）染色技术进行检查，然后显微镜检查隐孢子虫感染情况。
共检查了150名儿童，其中70名出现腹泻。腹泻儿童中隐孢子虫的患病率为19/70（27.1%），高于无腹泻儿童7/80（8.8%）。在科斯蒂教学医院，5岁以下儿童中隐孢子虫的患病率与腹泻的存在之间存在显著关系（P<0.05）。发现使用管道水源饮水的儿童患病率更高。
入住科斯蒂教学医院的儿童中检测到的寄生虫总体患病率为17.3%。腹泻儿童中的感染患病率为27.1%。研究腹泻儿童中隐孢子虫病的患病率可能有助于预测他们的健康状况，从而实现更好的诊断、治疗，进而改善患者状况。
