Iwasaki Masahiro, Murakami Masahiro, Ijiri Yoshinobu, Shimizu Muneshige, Yamamoto Junichiro
Division of Nutrition & Metabolism, Original Nutrition Co., Ltd, Osaka 532-0002, Japan.
Faculty of Pharmacy, Osaka Ohtani University, Osaka 584-8540, Japan.
Future Sci OA. 2020 Nov 9;7(2):FSO649. doi: 10.2144/fsoa-2020-0098.
Epidemiologic studies support the assumption (French paradox hypothesis) that drinking red wine is beneficial in the prevention of cardiovascular diseases. Our recent works however cast doubt on such claim. Earlier we have shown that the antithrombotic activity of various fruits and vegetables mainly depends on their varieties. For this reason, several varieties of red and white grapes were tested for antithrombotic effect in animal experiments.
Antithrombotic effect of 45 red and white grape varieties were assessed in the present study. Out of the 45, one red grape variety showed antithrombotic effect, while the majority of red and white grape varieties enhanced thrombosis.
Most red and white grape varieties enhanced thrombotic activity of blood.
流行病学研究支持饮用红酒对预防心血管疾病有益的假设（法国悖论假说）。然而，我们最近的研究对此说法提出了质疑。此前我们已经表明，各种水果和蔬菜的抗血栓活性主要取决于它们的品种。因此，在动物实验中对几种红葡萄和白葡萄品种的抗血栓作用进行了测试。
本研究评估了45个红葡萄和白葡萄品种的抗血栓作用。在这45个品种中，一个红葡萄品种显示出抗血栓作用，而大多数红葡萄和白葡萄品种增强了血栓形成。
大多数红葡萄和白葡萄品种增强了血液的血栓形成活性。
