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Taa 细胞与颗粒酶 K:老玩家,新把戏。

Taa Cells and Granzyme K: Old Players with New Tricks.

机构信息

Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.

出版信息

Immunity. 2021 Jan 12;54(1):6-8. doi: 10.1016/j.immuni.2020.12.008.

Abstract

Inflammaging is associated with chronic diseases, but tissue-specific changes in the immune system remain unknown. In this issue of Immunity, Mogilenko et al. use single-cell RNA sequencing, flow cytometry, and mass cytometry to describe age-related differences, including the accumulation of age-associated T cells that contribute to inflammaging.

摘要

炎症与慢性疾病有关,但免疫系统的组织特异性变化尚不清楚。在本期《免疫》杂志中,Mogilenko 等人使用单细胞 RNA 测序、流式细胞术和质谱流式细胞术来描述与年龄相关的差异,包括与炎症有关的与年龄相关的 T 细胞的积累。

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