Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
Immunity. 2021 Jan 12;54(1):6-8. doi: 10.1016/j.immuni.2020.12.008.
Inflammaging is associated with chronic diseases, but tissue-specific changes in the immune system remain unknown. In this issue of Immunity, Mogilenko et al. use single-cell RNA sequencing, flow cytometry, and mass cytometry to describe age-related differences, including the accumulation of age-associated T cells that contribute to inflammaging.
炎症与慢性疾病有关，但免疫系统的组织特异性变化尚不清楚。在本期《免疫》杂志中，Mogilenko 等人使用单细胞 RNA 测序、流式细胞术和质谱流式细胞术来描述与年龄相关的差异，包括与炎症有关的与年龄相关的 T 细胞的积累。
