Szeinberg A, Canny G J, Rashed N, Veneruso G, Levison H
Department of Respiratory Physiology, Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatr Pulmonol. 1988 Jan-Feb;4(1):8-12. doi: 10.1002/ppul.1950040104.
Lung function and maximal respiratory pressures of 24 adolescent females with mild-to-moderate idiopathic scoliosis (spinal curvature 10-60 degrees) were determined and compared with 38 age- and sex-matched controls. Twelve patients with moderate scoliosis (Cobb angle 35-60 degrees) had significantly reduced mean values for FVC (% predicted) and maximal inspiratory pressure (MIP), as compared to the controls. Twelve patients with mild scoliosis (Cobb angle less than 35 degrees) had normal mean values for FVC and maximal respiratory pressures, but five individual patients had FVC values less than 80% predicted. All but one of the patients with mild scoliosis had normal MIP values. FVC (% predicted) was significantly correlated with the degree of spinal curvature (r = -0.466; P less than 0.05) but was not related to MIP. These results indicate that reduced FVC values do occur in patients with mild-to-moderate idiopathic scoliosis and suggest that these low FVC values can be attributed to the rib cage deformity rather than to an inability to generate adequate inspiratory pressures.
测定了24名轻度至中度特发性脊柱侧凸（脊柱弯曲度为10至60度）的青春期女性的肺功能和最大呼吸压力，并与38名年龄和性别匹配的对照组进行了比较。与对照组相比，12名中度脊柱侧凸患者（Cobb角为35至60度）的FVC（预测值百分比）和最大吸气压力（MIP）平均值显著降低。12名轻度脊柱侧凸患者（Cobb角小于35度）的FVC和最大呼吸压力平均值正常，但有5名个体患者的FVC值低于预测值的80%。除1名患者外，所有轻度脊柱侧凸患者的MIP值均正常。FVC（预测值百分比）与脊柱弯曲程度显著相关（r = -0.466；P < 0.05），但与MIP无关。这些结果表明，轻度至中度特发性脊柱侧凸患者确实会出现FVC值降低的情况，并表明这些低FVC值可归因于胸廓畸形，而非无法产生足够的吸气压力。
