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新冠病毒在关键个人防护设备上的稳定性。

Stability of SARS-CoV-2 on critical personal protective equipment.

机构信息

National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada.

Department of Pediatrics and Child Health, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

出版信息

Sci Rep. 2021 Jan 13;11(1):984. doi: 10.1038/s41598-020-80098-3.

Abstract

The spread of COVID-19 in healthcare settings is concerning, with healthcare workers representing a disproportionately high percentage of confirmed cases. Although SARS-CoV-2 virus has been found to persist on surfaces for a number of days, the extent and duration of fomites as a mode of transmission, particularly in healthcare settings, has not been fully characterized. To shed light on this critical matter, the present study provides the first comprehensive assessment of SARS-CoV-2 stability on experimentally contaminated personal protective equipment (PPE) widely used by healthcare workers and the general public. Persistence of viable virus was monitored over 21 days on eight different materials, including nitrile medical examination gloves, reinforced chemical resistant gloves, N-95 and N-100 particulate respirator masks, Tyvek, plastic, cotton, and stainless steel. Unlike previous reports, viable SARS-CoV-2 in the presence of a soil load persisted for up to 21 days on experimentally inoculated PPE, including materials from filtering facepiece respirators (N-95 and N-100 masks) and a plastic visor. Conversely, when applied to 100% cotton fabric, the virus underwent rapid degradation and became undetectable by TCID assay within 24 h. These findings underline the importance of appropriate handling of contaminated PPE during and following use in high-risk settings and provide interesting insight into the potential utility of cotton in limiting COVID-19 transmission.

摘要

新冠病毒在医疗机构中的传播令人担忧,医护人员确诊病例的比例过高。尽管已经发现 SARS-CoV-2 病毒在表面上可以存活数天,但作为一种传播途径的污染物的程度和持续时间,特别是在医疗机构中,尚未得到充分描述。为了阐明这一关键问题,本研究首次全面评估了 SARS-CoV-2 在广泛应用于医护人员和公众的实验性污染个人防护装备(PPE)上的稳定性。在 21 天的时间里,监测了八种不同材料上存活病毒的情况,包括丁腈医用检查手套、加强型耐化学手套、N-95 和 N-100 颗粒物防护口罩、特卫强、塑料、棉花和不锈钢。与之前的报告不同,在存在土壤负荷的情况下,实验接种的 PPE 上的存活 SARS-CoV-2 可长达 21 天,包括过滤面罩呼吸器(N-95 和 N-100 口罩)和塑料面罩上的材料。相反,当应用于 100%棉织物时,病毒在 24 小时内迅速降解,TCID 检测不到。这些发现强调了在高风险环境中使用和使用后正确处理污染 PPE 的重要性,并为棉花在限制 COVID-19 传播方面的潜在用途提供了有趣的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01f2/7806900/ec8a46c09f17/41598_2020_80098_Fig1_HTML.jpg

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