Department of Rheumatology, Rehabilitation and Internal Diseases, Poznan University of Medical Sciences, Poznan, Poland.
Clin Interv Aging. 2021 Jan 7;16:43-56. doi: 10.2147/CIA.S268607. eCollection 2021.
SARS-CoV-2 infection is currently the most significant public health challenge. Its presentation ranges from mild to severe respiratory failure and septic shock. Rapid transmission of the virus is dangerous with a high possibility of life-threatening complications. Lack of treatment standards for SARS-CoV-2 is responsible for the current dilemma in clinical medicine.
An electronic literature search was done using PubMed to gather information on the pathogenesis, transmission of infection, clinical symptoms, diagnosis, and therapeutic options for COVID-19. Search items included "SARS-CoV-2", "COVID-19" and "coronavirus infection".
In light of the current global crisis caused by SARS-CoV-2, the exchange of information within the scientific community should be quick and extremely transparent. Thus, this review presents the available information necessary for a general practitioner. Such presentation of data should allow the reader quick access to basic and crucial information related to epidemiology, viral transmission, clinical symptoms, diagnostics, treatment, and complications that may occur in the course of COVID-19.
Rapidly increasing amounts of information about the diagnosis and treatment of patients with SARS-CoV-2 allow a better understanding of the etiology and course of the infection. In the current epidemiological situation, readily accessible information helps minimize the time to acquire knowledge and focus on prevention methods, diagnostic and treatment options. Thus, this review highlights key issues related to SARS-CoV-2 infection and contains the most useful data for daily medical practice.
目前,严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)感染是对公共卫生最大的挑战。其临床表现从轻症到严重呼吸衰竭和感染性休克不等。病毒的快速传播很危险,有很高的危及生命的并发症的可能性。缺乏针对 SARS-CoV-2 的治疗标准是目前临床医学面临的困境。
利用 PubMed 进行电子文献检索,收集有关 COVID-19 的发病机制、感染传播、临床症状、诊断和治疗选择的信息。检索项包括“SARS-CoV-2”“COVID-19”和“冠状病毒感染”。
鉴于目前由 SARS-CoV-2 引起的全球危机,科学界内部的信息交流应该迅速且极其透明。因此,这篇综述介绍了全科医生所需的现有信息。这种数据呈现方式应使读者能够快速访问与 COVID-19 相关的流行病学、病毒传播、临床症状、诊断、治疗和可能发生的并发症的基本和关键信息。
关于 SARS-CoV-2 患者的诊断和治疗的信息量迅速增加,有助于更好地了解感染的病因和病程。在当前的流行病学形势下,易于获取的信息有助于缩短获取知识的时间,并专注于预防方法、诊断和治疗选择。因此,本综述突出了与 SARS-CoV-2 感染相关的关键问题,并包含了日常医疗实践中最有用的数据。