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新型冠状病毒的重要性日益增加。

The increasing importance of the novel Coronavirus.

机构信息

Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, University City , Sharjah, United Arab Emirates.

出版信息

Hosp Pract (1995). 2021 Feb;49(1):1-11. doi: 10.1080/21548331.2020.1828888. Epub 2020 Oct 20.

Abstract

Coronavirus disease 2019 (COVID-19) instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more`` than 20 million people, with more than more than 700000 deaths globally; and has been declared a pandemic. SARS-CoV-2 is recognized as the seventh coronavirus affecting . The symptoms of COVID-19 consist of an elevated temperature, cough, diarrhea, and vomiting amongst others, whereas the transmission of SARS-CoV-2 is believed to arise via release of respiratory secretions; through sneezing and coughing. COVID-19 is identified via X-ray or computed tomography scans and further corroborated with molecular diagnostics techniques, including polymerase chain reaction. At present there are no successful therapeutics against SARS-CoV-2; existing antiviral therapies have been utilized to hinder manifestation of respiratory difficulties by diminishing viral load. Herein, we depict an extensive update on the clinical aspects of COVID-19, including strategies for the regulation of the transmission, diagnosis, treatment, and pathogenesis of SARS-CoV-2 infections.

摘要

新型冠状病毒病 2019(COVID-19)由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引发,已在全球感染超过 2000 万人,造成超过 70 万人死亡,并已宣布为大流行。SARS-CoV-2 被认为是第七种感染人类的冠状病毒。COVID-19 的症状包括体温升高、咳嗽、腹泻和呕吐等,而 SARS-CoV-2 的传播被认为是通过释放呼吸道分泌物;通过打喷嚏和咳嗽。COVID-19 通过 X 射线或计算机断层扫描进行识别,并通过聚合酶链反应等分子诊断技术进一步证实。目前,针对 SARS-CoV-2 没有成功的治疗方法;现有的抗病毒疗法已被用于通过减少病毒载量来阻止呼吸道困难的表现。在此,我们详细介绍了 COVID-19 的临床方面,包括对 SARS-CoV-2 感染的传播、诊断、治疗和发病机制的调节策略。

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