• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

模仿发作性睡病的心因性发作

Psychogenic Seizure Imitating Narcolepsy.

作者信息

Diukova Galina M, Makarov Sergey A, Golubev Valery L, Tyutina Ruslana R, Degterev Daniil A, Danilov Alexey B

机构信息

Neurological Department, Moscow Clinical Research Center, Moscow, Russian Federation.

Department of Nervous Disease, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.

出版信息

Case Rep Neurol. 2020 Dec 11;12(3):472-481. doi: 10.1159/000510517. eCollection 2020 Sep-Dec.

DOI:10.1159/000510517
PMID:33442377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7772851/
Abstract

Psychogenic or functional neurological disorders (FND) often occur in the practice of a neurologist. Diagnosis of FND usually causes significant difficulties. Among FND, psychogenic non-epileptic seizures (PNES) comprise around 40% cases. Sometimes it is necessary to differentiate PNES from narcolepsy. We describe a 55-year-old man with frequent brief and sudden sleep-like attacks in combination with nocturnal sleep disturbance. During attacks he was unresponsive, snoring but maintained posture. He resisted passive eye opening but with rolling eyes. The patient was confused on waking. In the interictal period, there were FND signs including give-way weakness of the left hand, typical functional "leg-dragging" gait, mistake in the finger-to-nose test. Video-electroencephalogram monitoring did not detect specific epileptic activity or sleep pattern during the attacks. Polysomnography showed multiple waking episodes during the night, but no typical pattern of narcolepsy was found in the multiple sleep latency test. The patient had frequent urgent hospitalizations due to different diseases and numerous invasive procedures. Six month later, the patient obtained state related disability financial benefit, after which hospitalizations in various hospitals continued, and PNES became shorter and less pronounced.

摘要

心因性或功能性神经障碍(FND)在神经科医生的临床实践中经常出现。FND的诊断通常会带来很大困难。在FND中,心因性非癫痫性发作(PNES)约占40%的病例。有时有必要将PNES与发作性睡病区分开来。我们描述了一名55岁男性,他频繁出现短暂且突然的类似睡眠的发作,并伴有夜间睡眠障碍。发作期间,他无反应、打鼾,但能保持姿势。他抗拒被动睁眼,但眼球转动。患者醒来时感到困惑。在发作间期,存在FND体征,包括左手的退让性无力、典型的功能性“拖腿”步态、指鼻试验错误。视频脑电图监测在发作期间未检测到特定的癫痫活动或睡眠模式。多导睡眠图显示夜间有多次觉醒发作,但在多次睡眠潜伏期试验中未发现发作性睡病的典型模式。该患者因各种疾病频繁紧急住院,并接受了大量侵入性检查。6个月后,患者获得了国家相关残疾抚恤金,此后在多家医院的住院治疗仍在继续,PNES发作变得更短且不那么明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/64b4747754bc/crn-0012-0472-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/4836f9e0d3f8/crn-0012-0472-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/311204da0a88/crn-0012-0472-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/ac9743a55494/crn-0012-0472-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/64b4747754bc/crn-0012-0472-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/4836f9e0d3f8/crn-0012-0472-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/311204da0a88/crn-0012-0472-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/ac9743a55494/crn-0012-0472-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5f/7772851/64b4747754bc/crn-0012-0472-g04.jpg

相似文献

1
Psychogenic Seizure Imitating Narcolepsy.模仿发作性睡病的心因性发作
Case Rep Neurol. 2020 Dec 11;12(3):472-481. doi: 10.1159/000510517. eCollection 2020 Sep-Dec.
2
[Phenomenology and psychiatric origins of psychogenic non-epileptic seizures].[心因性非癫痫性发作的现象学与精神科起源]
Srp Arh Celok Lek. 2004 Jan-Feb;132(1-2):22-7. doi: 10.2298/sarh0402022r.
3
Psychogenic nonepileptic seizures mimicking gelastic seizures: A description of two cases.模仿痴笑发作的精神性非癫痫性发作:两例病例描述。
Epilepsy Behav Case Rep. 2015 Aug 15;4:67-9. doi: 10.1016/j.ebcr.2015.06.003. eCollection 2015.
4
Sleep in psychogenic nonepileptic seizures and related disorders.心因性非癫痫性发作及相关障碍中的睡眠
Clin EEG Neurosci. 2015 Jan;46(1):34-41. doi: 10.1177/1550059414560565. Epub 2014 Dec 21.
5
Psychogenic non-epileptic seizures: our video-EEG experience.心因性非癫痫性发作:我们的视频脑电图经验
Neurol Res. 2011 Sep;33(7):694-700. doi: 10.1179/1743132811Y.0000000003.
6
Time-frequency mapping of the rhythmic limb movements distinguishes convulsive epileptic from psychogenic nonepileptic seizures.节律性肢体运动的时频映射可区分癫痫性抽搐和非癫痫性精神运动发作。
Epilepsia. 2013 Aug;54(8):1402-8. doi: 10.1111/epi.12207. Epub 2013 May 3.
7
Seizures by the clock: Temporal patterns of psychogenic nonepileptic seizures.时钟性发作:精神性非癫痫性发作的时间模式。
Epilepsy Behav. 2017 Nov;76:71-75. doi: 10.1016/j.yebeh.2017.08.025. Epub 2017 Sep 11.
8
Terminology of psychogenic nonepileptic seizures.心因性非癫痫性发作的术语。
Epilepsia. 2015 Mar;56(3):e21-5. doi: 10.1111/epi.12911. Epub 2015 Jan 29.
9
Psychogenic nonepileptic seizure manifestations reported by patients and witnesses.患者和目击者报告的精神性非癫痫性发作表现。
Epilepsia. 2011 Nov;52(11):2028-35. doi: 10.1111/j.1528-1167.2011.03162.x. Epub 2011 Jul 18.
10
Comparison of heart rate variability parameters during complex partial seizures and psychogenic nonepileptic seizures.比较复杂部分性发作和心因性非癫痫性发作期间的心率变异性参数。
Epilepsia. 2012 Aug;53(8):1314-21. doi: 10.1111/j.1528-1167.2012.03518.x. Epub 2012 May 29.

引用本文的文献

1
The neurobiology of functional neurological disorders characterised by impaired awareness.以意识障碍为特征的功能性神经障碍的神经生物学
Front Psychiatry. 2023 Mar 16;14:1122865. doi: 10.3389/fpsyt.2023.1122865. eCollection 2023.

本文引用的文献

1
Nonepileptic seizures - objective phenomena.非癫痫性发作——客观现象。
Handb Clin Neurol. 2016;139:297-304. doi: 10.1016/B978-0-12-801772-2.00026-6.
2
The ICSD-3 and DSM-5 guidelines for diagnosing narcolepsy: clinical relevance and practicality.国际睡眠障碍分类第三版(ICSD - 3)和精神疾病诊断与统计手册第五版(DSM - 5)中发作性睡病的诊断指南:临床相关性与实用性
Curr Med Res Opin. 2016 Oct;32(10):1611-1622. doi: 10.1080/03007995.2016.1208643. Epub 2016 Jul 20.
3
Misdiagnosis of narcolepsy.发作性睡病的误诊
Sleep Breath. 2016 Dec;20(4):1277-1284. doi: 10.1007/s11325-016-1365-5. Epub 2016 Jun 23.
4
Minimum requirements for the diagnosis of psychogenic nonepileptic seizures: a staged approach: a report from the International League Against Epilepsy Nonepileptic Seizures Task Force.诊断心因性非癫痫性发作的最低要求:分阶段方法:国际抗癫痫联盟非癫痫性发作工作组的报告。
Epilepsia. 2013 Nov;54(11):2005-18. doi: 10.1111/epi.12356. Epub 2013 Sep 20.
5
Functional symptoms in neurology: mimics and chameleons.神经病学中的功能性症状:模仿者与变色龙
Pract Neurol. 2013 Apr;13(2):104-13. doi: 10.1136/practneurol-2012-000422.
6
Pseudonarcolepsy in an 11-year-old boy.
Clin Child Psychol Psychiatry. 2008 Oct;13(4):585-91. doi: 10.1177/1359104508090608.
7
Frequency of ICD-10 factitious disorder: survey of senior hospital consultants and physicians in private practice.
Psychosomatics. 2007 Jan-Feb;48(1):60-4. doi: 10.1176/appi.psy.48.1.60.
8
Practice parameters for the indications for polysomnography and related procedures: an update for 2005.多导睡眠图及相关检查适应证的实践参数:2005年更新版
Sleep. 2005 Apr;28(4):499-521. doi: 10.1093/sleep/28.4.499.
9
Clinical significance of recurrent psychogenic nonepileptic seizure status.复发性心因性非癫痫性发作状态的临床意义
J Neurol. 2003 Nov;250(11):1355-62. doi: 10.1007/s00415-003-0224-z.
10
Pseudo-narcolepsy: case report.假性发作性睡病:病例报告。
J Psychiatry Neurosci. 1999 Sep;24(4):348-50.