Department of Psychology, University of Oviedo, Plaza Feijoo, s/n, 33003, Oviedo, Spain.
Institute of Biotechnology, University of Oviedo, Campus del Cristo, Edificio Santiago Gascón, 33006, Oviedo, Spain.
Neurol Sci. 2021 Sep;42(9):3687-3694. doi: 10.1007/s10072-021-05044-1. Epub 2021 Jan 13.
The mild cognitive impairment (MCI) is a neurocognitive disorder which involves cognitive impairments beyond those expected for the age and education of the subject but are not significant enough to interfere with instrumental activities of daily living. The identification of individuals with MCI is particularly important for those who might benefit from new therapies. The aim of this work is to propose a comprehensive neuropsychological protocol to achieve early diagnosis of MCI.
A neuropsychological battery was created and administered to a sample of patients with MCI (n = 25) and healthy matched controls (n = 25).
Although memory decline is often the first sign preceding the appearance of MCI, significant differences in visuospatial tasks, naming abilities, and executive function can be demonstrated as well between MCI and controls.
A proper selection of cognitive measures within those included in the already-available neuropsychological batteries may provide a thorough assessment of MCI and allow its timely diagnosis.
轻度认知障碍（MCI）是一种神经认知障碍，涉及认知障碍超出了受试者的年龄和教育水平所预期的范围，但不足以干扰日常生活的工具性活动。识别 MCI 患者对于那些可能受益于新疗法的患者尤为重要。本工作旨在提出一种综合的神经心理学方案，以实现 MCI 的早期诊断。
创建了一个神经心理学测试组，并对一组 MCI 患者（n=25）和健康匹配的对照组（n=25）进行了测试。
尽管记忆衰退通常是 MCI 出现前的第一个迹象，但在 MCI 和对照组之间也可以显示出在视空间任务、命名能力和执行功能方面的显著差异。
在已经可用的神经心理学测试组中选择适当的认知测试，可以提供对 MCI 的全面评估，并允许其及时诊断。
