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[不同品系和不同年龄小鼠生精上皮干细胞的辐射敏感性]

[Radiosensitivity of stem cells in the spermatogenic epithelium of mice of different strains and different ages].

作者信息

Konopliannikova O A, Konopliannikov A G

出版信息

Radiobiologiia. 1988 Jan-Feb;28(1):31-5.

PMID:3344329
Abstract

In experiments on CBA and BALB/c male mice (3 months of age) and F1(CBA X C57BL/6) hybrids (at the age of 3, 12, and 24 months) a difference was noted in the radiosensitivity of spermatogenic epithelium stem cells displayed by the changes in their colony-forming ability in testicular tubules 42 days following local 60Co-gamma-irradiation. The older the hybrid mice the smaller was the number of spermatogenic epithelium stem cells.

摘要

在对CBA和BALB/c雄性小鼠(3月龄)以及F1(CBA×C57BL/6)杂种小鼠(3、12和24月龄)进行的实验中,通过局部60Co-γ射线照射42天后睾丸小管中生殖上皮干细胞集落形成能力的变化,发现了它们放射敏感性的差异。杂种小鼠年龄越大,生殖上皮干细胞数量越少。

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