[CBA和BALB/c两种品系小鼠骨髓中粒细胞-巨噬细胞前体（CFU-DC）的辐射敏感性及辐射后动态变化]
[Radiosensitivity and postirradiation dynamics of granulocyte-macrophage precursors (CFU-DC) in the bone marrow of 2 lines of mice--CBA and BALB/c].
作者信息
Kaplan V P, Konopliannikov A G, Kolesnikova A I
出版信息
Radiobiologiia. 1985 Jul-Aug;25(4):536-9.
PMID:4034946
Abstract
CFU-DC in the bone marrow of CBA and BALB/c mice, which are contrast in total radiosensitivity, have close characteristics: D0 is 1.35 and 1.32 Gy, respectively. The proliferation rate of CFU-DC after single exposure to a non-lethal dose of 4 Gy is higher in CBA than in BALB/c mice. The time of doubling the CFU-DC population during the period of exponential growth after irradiation is 40 and 72 h for CBA and BALB/c mice, respectively.
摘要
在总体辐射敏感性上存在差异的CBA和BALB/c小鼠的骨髓中，集落形成单位来源的树突状细胞（CFU-DC）具有相近的特征：D0分别为1.35和1.32 Gy。单次接受4 Gy非致死剂量照射后，CBA小鼠中CFU-DC的增殖率高于BALB/c小鼠。照射后指数生长期内CFU-DC群体倍增时间，CBA小鼠为40小时，BALB/c小鼠为72小时。
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