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[高温(41.5℃,30分钟)对小鼠生精上皮干细胞的放射增敏作用]

[Radiosensitizing effect of hyperthermia (41.5C, 30 min) in stem cells of mouse spermatogenic epithelium].

作者信息

Lebedeva T V, Konopliannikova O A

出版信息

Radiats Biol Radioecol. 1993 Jul-Aug;33(4):564-6.

PMID:8401879
Abstract

Mouse testes preheated up to 41.5 degrees C for 30 min exhibit an increased radiosensitivity of testis epithelium stem cells. High death rate is described by a shift (by approximately 4 Gy) in the "dose-response" curve to the Abscissa left. The DMF value for hyperthermia depends on the cell survival rate, at which calculations are made, and varies from 2.1 to 1.4 within the range under study.

摘要

预热至41.5摄氏度并持续30分钟的小鼠睾丸,其睾丸上皮干细胞的放射敏感性增加。“剂量-反应”曲线向左横坐标方向移动(约4 Gy)表明死亡率很高。热疗的DMF值取决于进行计算时的细胞存活率,在所研究的范围内,其值在2.1至1.4之间变化。

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