Schultz R D, Sterpetti A V, Feldhaus R J
Department of Surgery, Creighton University, Omaha, Nebraska 68114.
Surg Gynecol Obstet. 1988 Mar;166(3):245-51.
Experience with carotid endarterectomy (CE) in patients 80 years of age and older is analyzed by reviewing results in terms of patient survival, quality of life and recurrence of symptoms of cerebral ischemia. During a 12 year period, 90 octogenarians underwent CE. Ages ranged from 80 to 93 years with a mean of 83 years. Two groups of patients younger than 80 years of age were selected from the series for comparison. There were no differences between age groups with respect to operative mortality and morbidity, with two deaths and one stroke in the elderly group. Follow-up periods ranged from one to 120 months with a mean of 39 months. There were two late strokes in patients older than 80 years of age. At late follow-up study, 87 per cent of patients operated upon for hemispheric symptoms were free of neurologic deficits; in contrast, only 67 per cent of those operated upon for nonhemispheric symptoms were symptom-free (p less than 0.05). The incidence of occlusive disease of the intracranial portion of the internal carotid artery was higher in the elderly group (p less than 0.01). The presence of intracranial occlusive disease represented an unfavorable factor in regard to the results of CE in patients with nonhemispheric symptoms. The over-all five year survival rate was 60 per cent. These data indicate that advanced age alone should not be considered a contraindication to CE. Excellent results should be expected in instances of operations performed for hemispheric symptoms. In instances of nonhemispheric symptoms, results are less encouraging because of the high incidence of intracranial carotid occlusive disease.
通过回顾80岁及以上患者的颈动脉内膜切除术(CE)在患者生存、生活质量和脑缺血症状复发方面的结果,对该手术经验进行了分析。在12年期间,90名八旬老人接受了CE手术。年龄范围为80至93岁,平均年龄为83岁。从该系列中选取两组年龄小于80岁的患者进行比较。各年龄组在手术死亡率和发病率方面无差异,老年组有2例死亡和1例中风。随访期为1至120个月,平均为39个月。80岁以上患者中有2例晚期中风。在晚期随访研究中,因半球症状接受手术的患者中有87%无神经功能缺损;相比之下,因非半球症状接受手术的患者中只有67%无症状(p<0.05)。老年组颈内动脉颅内段闭塞性疾病的发生率更高(p<0.01)。颅内闭塞性疾病的存在对于非半球症状患者的CE结果是一个不利因素。总体五年生存率为60%。这些数据表明,不应仅将高龄视为CE的禁忌症。对于因半球症状进行的手术,应预期会有良好的结果。对于非半球症状的情况,由于颅内颈动脉闭塞性疾病的高发生率,结果不太乐观。