Prenner K, Rendl K H, Paulowitz H P, Naglik H, Kos W, Ladurner G
Gefässchirurgische Abteilung, Landeskrankenanstalten Salzburg.
Wien Klin Wochenschr. 1992;104(15):482-8.
In a retrospective study we analysed two groups each consisting of 100 consecutive patients of similar age and sex distribution who underwent surgery for carotid disease with an intervening period of 5 years (group A 1980/82, group B 1986/87) between the collectives. Against a background of changing indications, tactics and techniques the aim of the study was to detect any differences between the two groups. Group A had a higher proportion of coronary and peripheral vascular disease. The states of cerebral ischemia I, II and III were distributed equally, but state IV was seen more frequently in group B (p less than 0.05). The number of shunt/without shunt operations in group A was 97/2, in group B 10/84 (p less than 0.005). The external carotid artery was deobliterated in 58/81 cases group A versus group B (p less than 0.005). We closed the artery by direct suture in 8/31 (p less than 0.005), by autologous venous patch in 53/26 (p less than 0.005) and by Dacron patches in 39/41 patients. In group A the operative mortality was zero and in group B 1 patient died; one patient in group B developed sudden occlusion (with TIA) postoperatively. Transient intra-/postoperative neurological deficits occurred in 1/2, permanent in 4/2 patients (n.s.). 54/25 patients have died up to 31/08/91. Coronary heart disease was the main cause of late complications and deaths in group A (p less than 0.025). Statistically, there was no dependence of neurological deficits on group, sex, age or intraoperative management. Only patients with preoperative PRINDS hat a higher postoperative neurological deficit rate than the others.
在一项回顾性研究中,我们分析了两组患者,每组各有100例年龄和性别分布相似的连续患者,他们均接受了颈动脉疾病手术,两组患者的收集时间间隔为5年(A组为1980/82年,B组为1986/87年)。在适应症、策略和技术不断变化的背景下,本研究的目的是检测两组之间的任何差异。A组中患有冠状动脉和外周血管疾病的比例更高。脑缺血I、II和III级的情况分布相同,但IV级在B组中更为常见(p<0.05)。A组中分流/无分流手术的数量为97/2,B组为10/84(p<0.005)。A组81例中有58例与B组相比颈外动脉再通(p<0.005)。我们通过直接缝合在8/31例中闭合动脉(p<0.005),通过自体静脉补片在53/26例中(p<0.005),并通过涤纶补片在39/41例患者中。A组手术死亡率为零,B组有1例患者死亡;B组有1例患者术后发生突然闭塞(伴有短暂性脑缺血发作)。术后短暂性神经功能缺损发生在1/2例中,永久性神经功能缺损发生在4/2例中(无统计学意义)。截至1991年8月31日,54/25例患者死亡。冠心病是A组晚期并发症和死亡的主要原因(p<0.025)。统计学上,神经功能缺损与分组、性别、年龄或术中管理无关。只有术前有PRINDS的患者术后神经功能缺损率高于其他患者。