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临床打印:从医学模型到器官植入物

Printing@Clinic: From Medical Models to Organ Implants.

作者信息

Zhao HaiMing, Yang FeiFei, Fu JianZhong, Gao Qing, Liu An, Sun Miao, He Yong

机构信息

Department of Vascular Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.

Department of Oral and Maxillofacial Surgery, The Affiliated Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.

出版信息

ACS Biomater Sci Eng. 2017 Dec 11;3(12):3083-3097. doi: 10.1021/acsbiomaterials.7b00542. Epub 2017 Oct 10.

Abstract

Since 1989, three-dimensional (3D) printing has developed rapidly in biomedical engineering because it is individually customizable. By printing medical products at clinics, this powerful tool can be used by doctors, which will enhance the response to surgery and increase the creative freedom of surgeons. In this article, we reviewed the progress of 3D printing in biomedicine with particular emphasis on the types of 3D printing methods that are most suitable for the clinical application, and proposed the concept of Printing@clinic. The four levels of Printing@clinic are discussed, from surgical implants to direct printing during surgery. Three major applications of Printing@clinic, which could be rapidly implemented in the clinical setting, are fabricating prosthesis to assist with surgeries, printing 3D implantable scaffolds, and bioprinting for tissue repair. We believe that Printing@clinic will be an attractive service in the decades to come.

摘要

自1989年以来,三维(3D)打印技术在生物医学工程领域发展迅速,因为它可以实现个性化定制。通过在诊所打印医疗产品,医生可以使用这个强大的工具,这将提高手术响应能力,并增加外科医生的创作自由度。在本文中,我们回顾了3D打印在生物医学领域的进展,特别强调了最适合临床应用的3D打印方法类型,并提出了“临床打印”(Printing@clinic)的概念。本文讨论了“临床打印”的四个层次,从手术植入物到手术过程中的直接打印。“临床打印”的三个主要应用,可在临床环境中迅速实现,包括制造辅助手术的假体、打印3D可植入支架以及用于组织修复的生物打印。我们相信,在未来几十年里,“临床打印”将成为一项有吸引力的服务。

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