• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

3D打印技术在骨外科手术中的应用前景

Perspectives of 3D printing technology in orthopaedic surgery.

作者信息

Zamborsky R, Kilian M, Jacko P, Bernadic M, Hudak R

出版信息

Bratisl Lek Listy. 2019;120(7):498-504. doi: 10.4149/BLL_2019_079.

DOI:10.4149/BLL_2019_079
PMID:31602984
Abstract

Using most widespread technology of rapid prototyping (RP) in medicine focus on the development of models for diagnosis, for training and planned surgery, as well as the direct manufacture of implants for bone reconstruction. The applications of 3D printing in the field of medicine are giving extraordinary results and tissue and prosthetic 3D printing, medical and engineering research professionals are conducting 3D printing organ bind. Researchers worldwide are pursuing the creation of artificial bone using 3D printers, bones that can be later implanted to humans. In near future, many body parts could be manufactured in a turn and successfully implanted to patients. Although medical advances in 3D printing are used in orthopaedic field, research in 4D printing has already started. Flat objects made with 3D printing, using a regular plastic, combined with smart material, were able to become a hub without an external intervention. In nutshell, the future of additive manufacturing (AM) in trauma and orthopedic surgery is relatively bright with the inclusion of 3D printing in medicine. Bioprinting in this area will be focused on fractures, nonunions, deformities and bone, cartilage and soft tissue reconstruction. CONCLUSION: The innovative technology not only assists the medical staff but is also beneficial for the patients because the medical problems, which were not curable in the past, are now possible with modern technology (Fig. 4, Ref. 52) Keywords: bone defect, tissue engineering, 3D printing, biomaterials, bone, porous scaffold.

摘要

医学领域中使用最广泛的快速成型(RP)技术主要集中在开发用于诊断、培训和手术规划的模型,以及直接制造用于骨重建的植入物。3D打印在医学领域的应用取得了非凡成果,组织和假体3D打印方面,医学和工程研究专业人员正在进行3D打印器官绑定。世界各地的研究人员都在致力于使用3D打印机制造人造骨,这种骨头随后可植入人体。在不久的将来,许多身体部位都可以批量制造并成功植入患者体内。尽管3D打印的医学进展已应用于骨科领域,但4D打印的研究已经开始。用3D打印制造的扁平物体,使用普通塑料并结合智能材料,能够在无需外部干预的情况下变成一个枢纽。简而言之,随着3D打印在医学中的应用,增材制造(AM)在创伤和骨科手术中的前景相对光明。该领域的生物打印将集中于骨折、骨不连、畸形以及骨、软骨和软组织重建。结论:这项创新技术不仅有助于医护人员,对患者也有益,因为过去无法治愈的医学问题现在借助现代技术成为可能(图4,参考文献52)关键词:骨缺损、组织工程、3D打印、生物材料、骨、多孔支架

相似文献

1
Perspectives of 3D printing technology in orthopaedic surgery.3D打印技术在骨外科手术中的应用前景
Bratisl Lek Listy. 2019;120(7):498-504. doi: 10.4149/BLL_2019_079.
2
Three-dimensional Bioprinting for Bone and Cartilage Restoration in Orthopaedic Surgery.三维生物打印在骨科手术中骨和软骨修复的应用。
J Am Acad Orthop Surg. 2019 Mar 1;27(5):e215-e226. doi: 10.5435/JAAOS-D-17-00632.
3
Three-dimensional Printing in Orthopaedic Surgery: Current Applications and Future Developments.三维打印在骨科手术中的应用:现状与未来发展。
J Am Acad Orthop Surg Glob Res Rev. 2021 Apr 20;5(4):e20.00230-11. doi: 10.5435/JAAOSGlobal-D-20-00230.
4
3D Bioprinting Technologies for Tissue Engineering Applications.三维生物打印技术在组织工程中的应用。
Adv Exp Med Biol. 2018;1078:15-28. doi: 10.1007/978-981-13-0950-2_2.
5
Tissue Engineering Applications of Three-Dimensional Bioprinting.三维生物打印的组织工程应用
Cell Biochem Biophys. 2015 Jul;72(3):777-82. doi: 10.1007/s12013-015-0531-x.
6
3D printing for clinical application in otorhinolaryngology.用于耳鼻咽喉科临床应用的3D打印技术。
Eur Arch Otorhinolaryngol. 2017 Dec;274(12):4079-4089. doi: 10.1007/s00405-017-4743-0. Epub 2017 Sep 19.
7
Smart biomaterials: From 3D printing to 4D bioprinting.智能生物材料:从 3D 打印到 4D 生物打印。
Methods. 2022 Sep;205:191-199. doi: 10.1016/j.ymeth.2022.07.006. Epub 2022 Jul 8.
8
Organ Bioprinting: Are We There Yet?器官生物打印:我们做到了吗?
Adv Healthc Mater. 2018 Jan;7(1). doi: 10.1002/adhm.201701018. Epub 2017 Nov 29.
9
Advances in bioprinting using additive manufacturing.增材制造在生物打印中的应用进展。
Eur J Pharm Sci. 2020 Feb 15;143:105167. doi: 10.1016/j.ejps.2019.105167. Epub 2019 Nov 26.
10
Enabling personalized implant and controllable biosystem development through 3D printing.通过 3D 打印实现个性化植入物和可控制生物系统的开发。
Biotechnol Adv. 2018 Mar-Apr;36(2):521-533. doi: 10.1016/j.biotechadv.2018.02.004. Epub 2018 Feb 9.

引用本文的文献

1
Three-dimensional printing in modern orthopedic trauma surgery: a comprehensive analysis of technical evolution and clinical translation.现代骨科创伤手术中的三维打印:技术演变与临床转化的综合分析
Front Med (Lausanne). 2025 Jul 15;12:1560909. doi: 10.3389/fmed.2025.1560909. eCollection 2025.
2
Accuracy and cost comparison of 3D-printed guides in complex spinal deformity correction: direct vs indirect design.复杂脊柱畸形矫正中3D打印导板的准确性与成本比较:直接设计与间接设计
Front Bioeng Biotechnol. 2025 May 30;13:1611998. doi: 10.3389/fbioe.2025.1611998. eCollection 2025.
3
Current developments in 3D printing technology for orthopedic trauma: A review.
骨科创伤3D打印技术的当前发展:综述
Medicine (Baltimore). 2025 Mar 21;104(12):e41946. doi: 10.1097/MD.0000000000041946.
4
Elastic properties of 3D printed clavicles are closer to cadaveric bones of elderly donors than commercial synthetic bones.3D 打印锁骨的弹性特性更接近老年供体的尸体骨骼,而不是商业合成骨骼。
J Mech Behav Biomed Mater. 2024 Dec;160:106774. doi: 10.1016/j.jmbbm.2024.106774. Epub 2024 Oct 12.
5
Three-Dimensional Bioprinting: A Comprehensive Review for Applications in Tissue Engineering and Regenerative Medicine.三维生物打印:组织工程与再生医学应用综述
Bioengineering (Basel). 2024 Jul 31;11(8):777. doi: 10.3390/bioengineering11080777.
6
Topology-Optimized Splints vs Casts for Distal Radius Fractures: A Randomized Clinical Trial.拓扑优化夹板与石膏固定治疗桡骨远端骨折的随机临床试验
JAMA Netw Open. 2024 Feb 5;7(2):e2354359. doi: 10.1001/jamanetworkopen.2023.54359.
7
4D Printing in Biomedical Engineering: Advancements, Challenges, and Future Directions.生物医学工程中的4D打印:进展、挑战与未来方向。
J Funct Biomater. 2023 Jun 29;14(7):347. doi: 10.3390/jfb14070347.
8
The Changing Environment in Postgraduate Education in Orthopedic Surgery and Neurosurgery and Its Impact on Technology-Driven Targeted Interventional and Surgical Pain Management: Perspectives from Europe, Latin America, Asia, and The United States.骨科手术和神经外科研究生教育环境的变化及其对技术驱动的靶向介入和手术疼痛管理的影响:来自欧洲、拉丁美洲、亚洲和美国的观点。
J Pers Med. 2023 May 18;13(5):852. doi: 10.3390/jpm13050852.
9
Clinical Application of Personalized Digital Surgical Planning and Precise Execution for Severe and Complex Adult Spinal Deformity Correction Utilizing 3D Printing Techniques.利用3D打印技术进行个性化数字外科规划及精确执行在重度和复杂成人脊柱畸形矫正中的临床应用
J Pers Med. 2023 Mar 30;13(4):602. doi: 10.3390/jpm13040602.
10
Modified Masquelet Technique Assisting 3D Printed Elbow Prosthesis for Open Elbow Fracture with Severe Bone Defect: A Case Report and Technique Note.改良 Masquelet 技术辅助 3D 打印肘关节假体治疗伴有严重骨缺损的开放性肘关节骨折:病例报告和技术说明。
Orthop Surg. 2022 Dec;14(12):3423-3430. doi: 10.1111/os.13522. Epub 2022 Oct 20.