三维生物打印技术在组织工程中的应用。

3D Bioprinting Technologies for Tissue Engineering Applications.

机构信息

Laboratory of Tissue Engineering, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea.

Department of Biomedical Engineering, Catholic University of Daegu, Gyeongsan, South Korea.

出版信息

Adv Exp Med Biol. 2018;1078:15-28. doi: 10.1007/978-981-13-0950-2_2.

DOI:10.1007/978-981-13-0950-2_2

PMID:30357616

Abstract

Three-dimensional (3D) printing (rapid prototyping or additive manufacturing) technologies have received significant attention in various fields over the past several decades. Tissue engineering applications of 3D bioprinting, in particular, have attracted the attention of many researchers. 3D scaffolds produced by the 3D bioprinting of biomaterials (bio-inks) enable the regeneration and restoration of various tissues and organs. These 3D bioprinting techniques are useful for fabricating scaffolds for biomedical and regenerative medicine and tissue engineering applications, permitting rapid manufacture with high-precision and control over size, porosity, and shape. In this review, we introduce a variety of tissue engineering applications to create bones, vascular, skin, cartilage, and neural structures using a variety of 3D bioprinting techniques.

摘要

三维（3D）打印（快速原型制作或添加剂制造）技术在过去几十年中在各个领域受到了广泛关注。特别是 3D 生物打印的组织工程应用引起了许多研究人员的关注。通过生物材料（生物墨水）的 3D 生物打印产生的 3D 支架可实现各种组织和器官的再生和修复。这些 3D 生物打印技术可用于制造用于生物医学和再生医学以及组织工程应用的支架，可实现快速制造，并具有高精度和对尺寸、孔隙率和形状的控制。在本综述中，我们介绍了各种组织工程应用，使用各种 3D 生物打印技术来创建骨骼、血管、皮肤、软骨和神经结构。