Antifungal sesquiterpenes with post-harvest anthracnose control effect on bananas from the fungus .

To search for antifungal leads, the metabolites of an insect-derived fungus ZMT01 were investigated, providing five sesquiterpenes (), including new molecules microsphaeropsisins D and E ( and ). The evaluated antifungal activities which are higher than the positive control triadimefon include: and towards (MICs 50, 25 mg L; triadimefon 100 mg L); , , and towards (MICs 25, 12.5, 25, 25; triadimefon 50 mg L), , and towards (MICs 25, 12.5, 25; triadimefon 80 mg L), and towards (MICs 100, 100; triadimefon 150 mg L). The bioassay displayed that the banana anthracnose control effect of (100 mg L) was also higher than that of triadimefon (Inhibition ratios 27.5 ± 2.5%, 55.3 ± 1.4%, 52.1 ± 1.3% for , 22.5 ± 2.1%, 47.2 ± 2.0%, 36.6 ± 2.2% for triadimefon at 4 d, 8 d and 12 d, respectively).[Formula: see text].