Sesquiterpenes with Phytopathogenic Fungi Inhibitory Activities from Fungus from Sonn.

A new monosesquiterpene diacetylgliocladic acid (), a new dimeric sesquiterpene divirensol H (), and two exceptionally novel trimeric sesquiterpene trivirensols A and B ( and ), together with another eight known congeners, were purified from an endophytic fungus FY06, derived from Sonn. whose fruit is a delicious and popular food. All of them were identified by comprehensive spectroscopic analysis, combined with biosynthetic considerations. Trivirensols A and B are unprecedented trimers of which three subunits are connected by two ester bonds of the sesquiterpene class. Relative to the positive control triadimefon, all the tested metabolites showed strong inhibitory activities against at least one phytopathogenic fungus among , , , , and . Notably, as metabolites of the endophytic fungus from , they all presented strong antifungal activities against which causes anthracnose in .