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一项使用多种量表评估不同疾病阶段双相情感障碍患者洞察力的对比研究。

A comparative study evaluating insight in different phase of illness among patients with bipolar disorder by using multiple scales.

机构信息

Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Nord J Psychiatry. 2021 Jul;75(5):378-388. doi: 10.1080/08039488.2020.1871068. Epub 2021 Jan 15.

Abstract

AIM

This cross-sectional study aimed to evaluate insight and its correlates among patients with bipolar disorder (BD).

METHODOLOGY

180 patients with BD were evaluated on Scale to Assess Unawareness of Mental Disorders (SUMD), Insight scale for affective disorders (ISAD), Mood Disorders Insight Scale (MDIS), and Beck Cognitive Insight Scale (BCIS).

RESULTS

About half of the patients were in clinical remission ( = 94; 52.2%), one-fifth ( = 37; 20.55%) were in the phase of mania and one-fourth ( = 49; 27.2%) were in a depression. There was no significant difference in the level of insight between those in clinical remission and those in depression except for one of the domains of BCIS. Patients with mania had poorer insight compared to those in remission and depression. In terms of association of insight as assessed by different scales, in the whole sample and all the three subgroups, SUMD current and past scores had a significant positive correlation with the ISAD total score. In the whole sample, among patients currently in remission and those currently in depression, ISAD total score had significant negative correlation with MDIS total score. Poorer insight as assessed on SUMD (current and past), ISAD and MDIS was associated with poorer medication adherence.

CONCLUSION

The present study demonstrates that patients with mania have poor insight when compared to the patients in clinical remission and depression. The present study also demonstrates that the assessment of clinical insight is not affected much by the type of scale used.

摘要

目的

本横断面研究旨在评估双相情感障碍(BD)患者的自知力及其相关因素。

方法

对 180 名 BD 患者进行了评估,使用了精神障碍觉察量表(SUMD)、情感障碍自知力量表(ISAD)、心境障碍自知力量表(MDIS)和贝克认知洞察量表(BCIS)。

结果

约一半的患者处于临床缓解期( = 94;52.2%),五分之一( = 37;20.55%)处于躁狂期,四分之一( = 49;27.2%)处于抑郁期。除了 BCIS 的一个领域外,处于临床缓解期和抑郁期的患者在自知力水平上没有显著差异。与缓解期和抑郁期的患者相比,躁狂期的患者自知力较差。在不同量表评估的自知力相关性方面,在整个样本和所有三个亚组中,SUMD 当前和过去的分数与 ISAD 总分呈显著正相关。在整个样本中,在当前处于缓解期和当前处于抑郁期的患者中,ISAD 总分与 MDIS 总分呈显著负相关。SUMD(当前和过去)、ISAD 和 MDIS 评估的较差洞察与较差的药物依从性有关。

结论

本研究表明,与处于临床缓解期和抑郁期的患者相比,躁狂期的患者自知力较差。本研究还表明,评估临床洞察力受所使用量表类型的影响不大。

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