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支气管戈登菌所致起搏器相关性心内膜炎

Pacemaker-induced endocarditis by Gordonia bronchialis.

作者信息

Mormeneo Bayo Saray, Palacián Ruíz María Pilar, Asin Samper Uxua, Millán Lou María Isabel, Pascual Catalán Ascensión, Villuendas Usón María Cruz

机构信息

Servicio de Microbiología, Hospital Universitario Miguel Servet Zaragoza, Spain.

Servicio de Microbiología, Hospital Universitario Miguel Servet Zaragoza, Spain.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2021 Jan 11. doi: 10.1016/j.eimc.2020.11.010.

DOI:10.1016/j.eimc.2020.11.010
PMID:33446400
Abstract

PURPOSE

Gordonia species are known to be opportunistic human pathogens causing secondary infections. We present the second case in the world of endocarditis caused by Gordonia bronchialis and a review of all the cases of endocarditis caused by Gordonia spp.

METHODS

The identification was performed by matrix-assisted desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing were performed to confirm the identification. Antimicrobial susceptibility was performed by MIC test Strip on Mueller-Hinton agar supplemented with 5% defibrinated sheep blood according to Clinical and Laboratory Standards Institute.

RESULTS

Pacemaker-induced endocarditis due to Gordonia bronchialis infection was determined in an 88-year old woman. The patient was treated with ceftriaxone and ciprofloxacin until completing 6 weeks from the pacemaker explant with a good evolution.

CONCLUSION

The case presented supports the pathogenic role of Gordonia bronchialis as an opportunistic pathogen and highlights the high risk of suffering infections caused by environmental bacteria.

摘要

目的

戈登氏菌属是已知的可引起继发感染的机会性人类病原体。我们报告世界上第二例由支气管戈登氏菌引起的心内膜炎病例,并对戈登氏菌属引起的心内膜炎的所有病例进行综述。

方法

通过基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)进行鉴定,并进行16S rRNA基因测序以确认鉴定结果。根据临床和实验室标准协会的标准,在补充有5%去纤维羊血的Mueller-Hinton琼脂上使用MIC测试条进行药敏试验。

结果

一名88岁女性被确诊为因支气管戈登氏菌感染导致的起搏器相关性心内膜炎。患者接受头孢曲松和环丙沙星治疗,直至起搏器取出后6周,病情好转。

结论

该病例支持支气管戈登氏菌作为机会性病原体的致病作用,并强调了感染环境细菌的高风险。