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多参数磁共振成像在前列腺癌管理中的应用:最新进展——一篇叙述性综述

Multiparametric MRI in the management of prostate cancer: an update-a narrative review.

作者信息

Ziglioli Francesco, Maestroni Umberto, Manna Carmelinda, Negrini Giulio, Granelli Giorgia, Greco Valentina, Pagnini Francesco, De Filippo Massimo

机构信息

Department of Urology, University-Hospital of Parma, Parma, Italy.

Department of Radiology, University-Hospital of Parma, Parma, Italy.

出版信息

Gland Surg. 2020 Dec;9(6):2321-2330. doi: 10.21037/gs-20-561.

Abstract

The growing interest in multiparametric MRI is leading to important changes in the diagnostic process of prostate cancer. MRI-targeted biopsy is likely to become a standard for the diagnosis of prostate cancer in the next years. Despite it is well known that MRI has no role as a staging technique, it is clear that multiparametric MRI may be of help in active surveillance protocols. Noteworthy, MRI in active surveillance is not recommended, but a proper understanding of its potential may be of help in achieving the goals of a delayed treatment strategy. Moreover, the development of minimally invasive techniques, like laparoscopic and robotic surgery, has led to greater expectations as regard to the functional outcomes of radical prostatectomy. Multiparametric MRI may play a role in planning surgical strategies, with the aim to provide the highest oncologic outcome with a minimal impact on the quality of life. We maintain that a proper anatomic knowledge of prostate lesions may allow the surgeon to achieve a better result in planning as well as in performing surgery and help the surgeon and the patient engage in a shared decision in planning a more effective strategy for prostate cancer control and treatment. This review highlights the advantages and the limitations of multiparametric MRI in prostate cancer diagnosis, in active surveillance and in planning surgery.

摘要

对多参数磁共振成像(MRI)日益增长的兴趣正在导致前列腺癌诊断过程发生重大变化。MRI靶向活检很可能在未来几年成为前列腺癌诊断的标准。尽管众所周知MRI不作为分期技术,但很明显多参数MRI在主动监测方案中可能会有所帮助。值得注意的是,不建议在主动监测中使用MRI,但正确理解其潜力可能有助于实现延迟治疗策略的目标。此外,腹腔镜和机器人手术等微创技术的发展,使得人们对根治性前列腺切除术的功能结果有了更高的期望。多参数MRI可能在规划手术策略中发挥作用,目的是以对生活质量影响最小的方式提供最高的肿瘤学结果。我们认为,对前列腺病变有适当的解剖学知识可以使外科医生在手术规划以及手术操作中取得更好的结果,并帮助外科医生和患者共同做出决策,规划更有效的前列腺癌控制和治疗策略。本综述强调了多参数MRI在前列腺癌诊断、主动监测和手术规划中的优点和局限性。

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