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本文引用的文献

1
Combined drug repurposing and virtual screening strategies with molecular dynamics simulation identified potent inhibitors for SARS-CoV-2 main protease (3CLpro).联合药物重定位和虚拟筛选策略与分子动力学模拟鉴定出针对 SARS-CoV-2 主要蛋白酶(3CLpro)的有效抑制剂。
J Biomol Struct Dyn. 2021 Aug;39(13):4659-4670. doi: 10.1080/07391102.2020.1779128. Epub 2020 Jun 18.
2
Fragment Molecular Orbital Based Interaction Analyses on COVID-19 Main Protease - Inhibitor N3 Complex (PDB ID: 6LU7).基于片段分子轨道的 COVID-19 主蛋白酶-抑制剂 N3 复合物(PDB ID:6LU7)相互作用分析。
J Chem Inf Model. 2020 Jul 27;60(7):3593-3602. doi: 10.1021/acs.jcim.0c00283. Epub 2020 Jun 25.
3
Repurposing cefuroxime for treatment of COVID-19: a scoping review of studies.重新利用头孢呋辛治疗 COVID-19:研究的范围综述。
J Biomol Struct Dyn. 2021 Aug;39(12):4547-4554. doi: 10.1080/07391102.2020.1777904. Epub 2020 Jun 13.
4
Liu Shen capsule shows antiviral and anti-inflammatory abilities against novel coronavirus SARS-CoV-2 via suppression of NF-κB signaling pathway.柳参胶囊通过抑制 NF-κB 信号通路显示出对新型冠状病毒 SARS-CoV-2 的抗病毒和抗炎能力。
Pharmacol Res. 2020 Aug;158:104850. doi: 10.1016/j.phrs.2020.104850. Epub 2020 Apr 30.
5
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.基于结构的针对 SARS-CoV-2 主蛋白酶的抗病毒药物候选物的设计。
Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22.
6
A new coronavirus associated with human respiratory disease in China.一种在中国与人类呼吸道疾病相关的新型冠状病毒。
Nature. 2020 Mar;579(7798):265-269. doi: 10.1038/s41586-020-2008-3. Epub 2020 Feb 3.
7
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.新冠病毒的基因组特征和流行病学:对病毒起源和受体结合的影响。
Lancet. 2020 Feb 22;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8. Epub 2020 Jan 30.
8
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.中国武汉 99 例 2019 年新型冠状病毒肺炎患者的流行病学和临床特征:描述性研究。
Lancet. 2020 Feb 15;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7. Epub 2020 Jan 30.
9
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
10
Inhibition of SARS-CoV 3CL protease by flavonoids.黄酮类化合物对 SARS-CoV 3CL 蛋白酶的抑制作用。
J Enzyme Inhib Med Chem. 2020 Dec;35(1):145-151. doi: 10.1080/14756366.2019.1690480.

In silico and in vitro evaluation of kaempferol as a potential inhibitor of the SARS-CoV-2 main protease (3CLpro).

作者信息

Khan Abbas, Heng Wang, Wang Yanjing, Qiu Jingfei, Wei Xiaoyong, Peng Shaoliang, Saleem Shoaib, Khan Mazhar, Ali Syed Shujait, Wei Dong-Qing

机构信息

Department of Bioinformatics and Biological Statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Peng Cheng Laboratory, Shenzhen, China.

出版信息

Phytother Res. 2021 Jun;35(6):2841-2845. doi: 10.1002/ptr.6998. Epub 2021 Jan 15.

DOI:10.1002/ptr.6998
PMID:33448101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8013176/
Abstract
摘要