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基于 CT 标准的腋动脉或股动脉置管微创心脏手术的灌注策略:270 例患者的经验。

Perfusion strategy using axillary or femoral cannulation for minimally invasive cardiac surgery: experience in 270 patients with computed tomography-based criteria.

机构信息

Department of Cardiovascular Surgery, Chibanishi General Hospital, Matsudo-city, Chiba, Japan.

出版信息

Eur J Cardiothorac Surg. 2021 Jun 14;59(6):1200-1207. doi: 10.1093/ejcts/ezaa469.

Abstract

OBJECTIVES

In patients with atherosclerotic disease, minimally invasive cardiac surgery using retrograde perfusion for cardiopulmonary bypass via femoral cannulation (FC) carries a higher risk of brain embolization compared with antegrade perfusion. However, guidelines for selecting antegrade versus retrograde perfusion do not exist. We developed a computed tomography (CT)-based perfusion strategy and assessed outcomes.

METHODS

We studied 270 minimally invasive cardiac surgery patients, aged 68 ± 13, 124 female, body surface area 1.6 ± 0.2 m2. Antegrade perfusion using axillary cannulation (AC) was selected if any of the following preoperative enhanced CT scan criteria were satisfied anywhere in the aorta or iliac arteries: thrombosis thickness >3 mm, thrombosis >one-third of the total circumference and calcification present in the total circumference. FC was selected otherwise. Asymptomatic brain injury was assessed by diffusion-weighted magnetic resonance imaging.

RESULTS

AC and FC were selected in 95 (35%) and 175 patients, respectively. AC patients were 10 years older (P < 0.001) and had higher EuroSCORE II (2.7 ± 3.4 vs 1.7 ± 1.9, P = 0.002). The median cardiopulmonary time and cross-clamp times were not significantly different. No patients died in hospital. There was no immediate stroke in either group during 48 h after surgery. Asymptomatic brain injury was detected in 25 (26%) and 27 (15%) AC and FC patients, respectively, P = 0.03.

CONCLUSIONS

We believe our CT-based perfusion strategy using AC or FC minimized brain embolic rates. AC can be a good alternative to prevent brain embolization for minimally invasive cardiac surgery patients with advanced atherosclerotic disease.

摘要

目的

在患有动脉粥样硬化疾病的患者中,经股动脉插管(FC)逆行灌注行微创心脏手术的体外循环中,脑栓塞的风险高于顺行灌注。然而,目前尚不存在选择顺行或逆行灌注的指南。我们开发了一种基于计算机断层扫描(CT)的灌注策略,并评估了其结果。

方法

我们研究了 270 名年龄为 68±13 岁、124 名女性、体表面积为 1.6±0.2m2 的微创心脏手术患者。如果术前增强 CT 扫描在主动脉或髂动脉的任何部位满足以下任何标准,则选择腋动脉插管(AC)进行顺行灌注:血栓厚度>3mm、血栓>总周长的三分之一和总周长有钙化。否则,选择 FC。通过弥散加权磁共振成像评估无症状性脑损伤。

结果

95 例(35%)患者选择 AC,175 例(65%)患者选择 FC。AC 组患者年龄大 10 岁(P<0.001),EuroSCORE II 评分更高(2.7±3.4 比 1.7±1.9,P=0.002)。体外循环和主动脉阻断时间中位数无显著差异。两组患者均无院内死亡。两组患者术后 48 小时内均无即刻性中风。AC 组和 FC 组分别有 25 例(26%)和 27 例(15%)患者出现无症状性脑损伤,P=0.03。

结论

我们认为,我们使用 AC 或 FC 的基于 CT 的灌注策略最大限度地降低了脑栓塞的发生率。对于患有晚期动脉粥样硬化疾病的微创心脏手术患者,AC 可以作为预防脑栓塞的一种良好选择。

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