University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Eastern Colorado Veterans Affairs Geriatric Research, Education, and Clinical Center, Denver, CO, USA.
Curr Diab Rep. 2021 Jan 15;21(2):4. doi: 10.1007/s11892-020-01373-1.
This paper presents a review of the current literature in support of a model explaining the relationships between sleep health and risk for type 2 diabetes in adolescents.
Short sleep duration is associated with risk of developing obesity in youth. Sleep restriction increases energy expenditure, but also increases hunger, appetite, and food intake, causing positive energy balance, impacting appetite-regulating hormones, and leading to increased eating late at night. Insufficient sleep may lead to reduced physical activity and greater sedentary behaviors. In addition, short sleep duration is associated with reduced insulin sensitivity. The cumulative negative consequences of insufficient sleep increase risk for type 2 diabetes. Applications to clinical care, public policy, and future research are discussed. Insufficient sleep in adolescence increases risk for type 2 diabetes directly through impact on insulin sensitivity and indirectly through increased dietary intake, sedentary activity, and weight gain.
本文回顾了目前支持解释青少年睡眠健康与 2 型糖尿病风险之间关系的文献，提出了一个模型。
青少年睡眠时间短与肥胖风险相关。睡眠限制会增加能量消耗，但也会增加饥饿感、食欲和食物摄入，导致能量正平衡，影响食欲调节激素，并导致夜间进食增加。睡眠不足会导致体力活动减少和久坐行为增加。此外，睡眠时间短与胰岛素敏感性降低有关。睡眠不足的累积负面影响会增加 2 型糖尿病的风险。讨论了其在临床护理、公共政策和未来研究中的应用。青少年睡眠不足会直接通过影响胰岛素敏感性，间接通过增加饮食摄入、久坐活动和体重增加，增加 2 型糖尿病的风险。
