J Am Anim Hosp Assoc. 2021 Mar 1;57(2):96-100. doi: 10.5326/JAAHA-MS-7088.
A 5 mo old male intact English bulldog was evaluated at a veterinary referral hospital for acute respiratory distress and chronic difficulty breathing. Thoracic radiographs revealed multifocal pulmonary hyperinflation and hyperlucency suspected in the left caudal and accessory lung lobes. A thoracic computed tomography scan identified severe diffuse enlargement of the caudal subsegment of the left cranial lung lobe and the dorsal process of the accessory lung lobe, with parenchymal hypoattenuation, rounded margins, and thin pulmonary vessels. Based on clinical signs and imaging findings, he was diagnosed with suspect congenital lobar emphysema in multiple lung lobes. A median sternotomy was performed, which revealed a hyperinflated, emphysematous left cranial lung lobe (caudal subsegment) and accessory lung lobe for which two lung lobectomies were performed. The remaining lung lobes were small and atelectatic. Histopathology revealed bronchial cartilage hypoplasia and aplasia and findings consistent with congenital lobar emphysema. The puppy recovered well from surgical treatment of congenital lobar emphysema, requiring multiple lung lobectomies, with subsequent computed tomography-evidenced re-expansion of the remaining lung lobes 3 mo after surgery. The patient is still alive 1 yr after surgery with a normal activity level and no evidence of respiratory compromise.
一只 5 月龄雄性未去势英国斗牛犬因急性呼吸窘迫和慢性呼吸困难在兽医转诊医院接受评估。胸部放射照片显示左肺后叶和副肺叶多灶性肺过度充气和透亮。胸部计算机断层扫描发现左肺颅前段和副肺叶背侧支的严重弥漫性扩大，实质衰减、圆形边缘和细肺动脉。根据临床症状和影像学检查结果，怀疑该犬患有多肺叶先天性肺大疱。进行了正中胸骨切开术，发现左肺颅前段（后支）和副肺叶过度充气、气肿，对这两个肺叶进行了肺叶切除术。其余肺叶较小且肺不张。组织病理学显示支气管软骨发育不良和发育不全，与先天性肺大疱的发现一致。该犬在接受先天性肺大疱肺叶切除术治疗后恢复良好，需要进行多次肺叶切除术，术后 3 个月计算机断层扫描显示剩余肺叶重新扩张。手术后 1 年，该犬仍存活，活动水平正常，无呼吸窘迫迹象。
