Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, United States.
Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Epilepsy Behav. 2021 Feb;115:107734. doi: 10.1016/j.yebeh.2020.107734. Epub 2020 Dec 29.
The aim of the current study was to investigate the rates of contracting COVID-19 in various populations to provide evidence on the susceptibility of patients with epilepsy (PWE) to contracting symptomatic COVID-19.
We surveyed a random sample of three groups of people: patients with epilepsy, people with psychiatric problems, and a group of the general population. The survey included four general questions (age, sex, education, and medical/psychiatric problem) and four COVID-19 specific questions (contracting COVID-19, relatives with COVID-19, wearing a face mask, and frequent hand washings).
Three hundred and fifty -eight people were surveyed (108 healthy individuals, 154 patients with epilepsy, and 96 patients with psychiatric problems). Thirty-eight (11%) people had a history of COVID-19 contraction. The only factor that had a significant association with COVID-19 contraction was a relative with COVID-19 (Odds Ratio: 5.82; 95% Confidence Interval: 2.85-11.86; p = 0.0001). Having epilepsy did not increase the risk of COVID-19 contraction.
Symptomatic COVID-19 does not seem to be more likely in PWE. The single most important factor associated with contracting COVID-19 is a close relative with this infection. Isolation of people with SARS-CoV-2 infection and observation of their close contacts may reduce the risk of secondary infections.
本研究旨在调查不同人群感染 COVID-19 的比率，为癫痫患者（PWE）易感染有症状的 COVID-19 提供证据。
我们调查了三组随机人群：癫痫患者、精神问题患者和一般人群。调查包括四个一般问题（年龄、性别、教育程度和医疗/精神问题）和四个 COVID-19 特定问题（感染 COVID-19、有 COVID-19 亲属、戴口罩和经常洗手）。
共调查了 358 人（108 名健康个体、154 名癫痫患者和 96 名精神问题患者）。38 人（11%）有 COVID-19 感染史。唯一与 COVID-19 感染显著相关的因素是有 COVID-19 亲属（优势比：5.82；95%置信区间：2.85-11.86；p=0.0001）。患有癫痫并不会增加感染 COVID-19 的风险。
癫痫患者似乎不太容易感染有症状的 COVID-19。与感染 COVID-19 相关的最重要因素是有密切接触者感染该病毒。隔离 SARS-CoV-2 感染者并观察其密切接触者可能会降低二次感染的风险。
