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COVID-19 大流行期间的癫痫发作和癫痫的评估与治疗。

Evaluation and Treatment of Seizures and Epilepsy During the COVID-19 Pandemic.

机构信息

Department of Neurology, School of Medicine, University of Colorado, Aurora, CO, USA.

Comprehensive Epilepsy Center, School of Medicine, New York University, New York, NY, USA.

出版信息

Curr Neurol Neurosci Rep. 2022 Jan;22(1):11-17. doi: 10.1007/s11910-022-01174-x. Epub 2022 Jan 26.

DOI:10.1007/s11910-022-01174-x
PMID:35080752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8790547/
Abstract

PURPOSE OF REVIEW

Seizures, including status epilepticus, have been reported in association with acute COVID-19 infection. People with epilepsy (PWE) have suffered from seizure exacerbations during the pandemic. This article reviews the data for clinical and electrographic seizures associated with COVID-19, technical EEG considerations for reducing risk of transmission, and factors contributing to seizure exacerbations in PWE as well as strategies to address this issue.

RECENT FINDINGS

An increasing number of studies of larger cohorts, accounting for a variety of variables and often utilizing EEG with standardized terminology, are assessing the prevalence of seizures in hospitalized patients with acute COVID-19 infections, and gaining insight into the prevalence of seizures and their effect on outcomes. Additionally, recent studies are evaluating the effect of the pandemic on PWE, barriers faced, and the usefulness of telehealth. Although there is still much to learn regarding COVID-19, current studies help in assessing the risk of seizures, guiding EEG utilization, and optimizing the use of telehealth during the pandemic.

摘要

目的综述

有报道称,急性 COVID-19 感染可引起癫痫发作,包括癫痫持续状态。在大流行期间,癫痫患者 (PWE) 的癫痫发作加剧。本文综述了与 COVID-19 相关的临床和脑电图癫痫发作的数据、降低传播风险的技术脑电图注意事项,以及导致 PWE 癫痫发作加剧的因素和解决这一问题的策略。

最新发现

越来越多的研究对更大的队列进行了评估,考虑了各种变量,并且经常使用具有标准化术语的脑电图,以评估急性 COVID-19 感染住院患者癫痫发作的患病率,并深入了解癫痫发作的患病率及其对结局的影响。此外,最近的研究还评估了大流行对 PWE 的影响、面临的障碍以及远程医疗的实用性。尽管关于 COVID-19 仍有许多需要了解的地方,但目前的研究有助于评估癫痫发作的风险、指导脑电图的应用,以及在大流行期间优化远程医疗的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1f7/8790547/fdeb6a543149/11910_2022_1174_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1f7/8790547/fdeb6a543149/11910_2022_1174_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1f7/8790547/fdeb6a543149/11910_2022_1174_Fig1_HTML.jpg

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本文引用的文献

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Outcomes of seizures, status epilepticus, and EEG findings in critically ill patient with COVID-19.COVID-19 危重症患者的癫痫发作、癫痫持续状态和脑电图结果。
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Bioinformatics approach to identify the influences of SARS-COV2 infections on atherosclerosis.利用生物信息学方法确定SARS-CoV-2感染对动脉粥样硬化的影响。
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Electroencephalographic Abnormalities are Common in COVID-19 and are Associated with Outcomes.脑电图异常在 COVID-19 中很常见,并与结局相关。
Ann Neurol. 2021 May;89(5):872-883. doi: 10.1002/ana.26060. Epub 2021 Mar 24.
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COVID-19-Associated Neurological Manifestations: An Emerging Electroencephalographic Literature.新型冠状病毒肺炎相关神经表现:新兴的脑电图学文献
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