Assistant Lecturer, Oral Medicine and Periodontology, Alexandria University, Egypt.
Lecturer, Oral Medicine and Periodontology, Lecturer, Alexandria University, Egypt.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Mar;131(3):304-311. doi: 10.1016/j.oooo.2020.12.016. Epub 2020 Dec 20.
The objective of this study was to establish and validate a new scoring system for oral lichen planus (OLP).
Forty patients with erosive OLP were scored using a new proposed scoring system and the one suggested by Thongprasom. Statistical analysis was used to calculate inter- and intraexaminer reliability, validity, diagnostic accuracy, and clinical sensitivity for both scores.
Concurrent validity showed a significant strong correlation between pain scale and the new score (r = 0.846) versus Thongprasom's score (r = 0.665). Interexaminer agreement showed a statistically significant agreement with the biopsy results (kappa = 0.74) for the new score, whereas no agreement was evident with Thongprasom's score (kappa = 0.03163). The diagnostic accuracy of the new score was area under the curve = 0.839, whereas the diagnostic accuracy of Thongprasom's score was area under the curve = 0.667. Significant differences in the scores were detected while comparing the clinical sensitivity of both systems.
The new comprehensive scoring system could be a valid, reproducible, and sensitive tool to accurately assess the severity of OLP. In addition, the proposed scoring system is easily taught, is relatively faster to master, and does not require complicated calculations.
本研究旨在建立和验证一种新的口腔扁平苔藓（OLP）评分系统。
对 40 例糜烂性 OLP 患者使用新提出的评分系统和 Thongprasom 提出的评分系统进行评分。统计分析用于计算两种评分的组内和组间可靠性、有效性、诊断准确性和临床敏感性。
并行效度显示疼痛量表与新评分（r=0.846）与 Thongprasom 评分（r=0.665）之间存在显著的强相关性。组内一致性显示新评分与活检结果具有统计学显著一致性（kappa=0.74），而 Thongprasom 评分则没有明显的一致性（kappa=0.03163）。新评分的诊断准确性为曲线下面积为 0.839，而 Thongprasom 评分的诊断准确性为曲线下面积为 0.667。两种系统比较时，检测到评分存在显著差异。
新的综合评分系统可能是一种准确评估 OLP 严重程度的有效、可重复和敏感的工具。此外，所提出的评分系统易于教授，掌握起来相对较快，并且不需要复杂的计算。
