Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 1617, Section 1, Riyue Avenue, Qingyang District, Chengdu City, Sichuan Province, China.
Indian J Pediatr. 2021 Aug;88(8):753-756. doi: 10.1007/s12098-020-03649-6. Epub 2021 Jan 16.
To investigate the fractional exhaled nitric oxide (FeNO) normal value of healthy children, and provide a reliable theoretical basis for clinical diagnosis.
481 healthy children aged 6-15-y-old in three primary schools in Chengdu were subjected for FeNO detection. Through the statistical analysis, the upper limit normal value of FeNO among the healthy children was obtained, and the related influencing factors of FeNO value were analyzed.
Among the 481 heathy children, the geometric mean value of FeNO was 14.59 ppb (minimum value was 5 ppb, maximum value was 69 ppb), and the upper limit of normal value was 28 ppb. The age, height, and weight all have significant correlations with FeNO.
The upper limit of FeNO in healthy children aged 6-15-y-old was 28.0 ppb. Inflammation in the airway was suggested when the value of FeNO exceeds 28.0 ppb. Furthermore, the influencing factors such as age, weight, height must be considered.
探讨健康儿童呼出气一氧化氮（FeNO）的正常值，为临床诊断提供可靠的理论依据。
对成都市三所小学的 481 名 6-15 岁健康儿童进行 FeNO 检测。通过统计分析，得出健康儿童 FeNO 的上限正常值，并分析 FeNO 值的相关影响因素。
在 481 名健康儿童中，FeNO 的几何均数为 14.59 ppb（最小值为 5 ppb，最大值为 69 ppb），正常上限值为 28 ppb。年龄、身高、体重均与 FeNO 有显著相关性。
6-15 岁健康儿童的 FeNO 上限值为 28.0 ppb。当 FeNO 值超过 28.0 ppb 时，提示气道存在炎症。此外，还必须考虑年龄、体重、身高等影响因素。
